Protein Alignment CG18262 and ZNF836

DIOPT Version :10

• Sequence 1: NP_572453.1
• Gene: CG18262 / 31745
• FlyBaseID: FBgn0030012
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_001096127.1
• Gene: ZNF836 / 162962
• HGNCID: 34333
• Length: 936
• Species: Homo sapiens
• Alignment Length: 369
• Identity: 109/369 - (29%)
• Similarity: 167/369 - (45%)
• Gaps: 62/369 - (16%)

  Fly    73 AQDVVEVQGNEELHEELAKEASPDLEEEEEEKEEGSKRQHYQRAAAMKN-TLVETREDLLDIELD 136
            :|:.||   |:.:..:|.......|.|.::.:.||...:..|....:.| :||...:.:|.
Human   128 SQEDVE---NKCIENQLTLSFQSRLTELQKFQTEGKIYECNQSEKTVNNSSLVSPLQRILP---- 185

  Fly   137 WTGGEQSEHNETHEEEEGESDDDDTKDSNDTKDMLFQCDQCDRAYNTKRSLQSHRRLKHSEANGG 201
               ..|:..::.:|.|..:.......:....::..:.|..|.:|:....||.:|:.:..:|
Human   186 ---SVQTNISKKYENEFLQLSLPTQLEKTHIREKPYMCKGCGKAFRVSSSLINHQMVHTTE---- 243

  Fly   202 SLDKSASERNSKKRKGPPKVYKCNE--------------------------EACNQTFRTERDLR 240
                              |.|||||                          ..|.:.||...||.
Human   244 ------------------KPYKCNECGKAFHRGSLLTIHQIVHTRGKPYQCGVCGKIFRQNSDLV 290

  Fly   241 GHRWKHTG---IFCDICGKPFTQSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGR 302
            .||..|||   ..|:.|||.|:||.|:..|::.|:|.||:||.||..||.....|::|.|.|||.
Human   291 NHRRSHTGEKPYKCNECGKSFSQSYNLAIHQRIHTGEKPYKCNECGKTFKQGSCLTTHQIIHTGE 355

  Fly   303 MPCICEVCGRPCRDRGVLTAHMRRHTGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCG 367
            .|..|::||:..|....|..|.|.||||:|.||.:|||:|....:|..|...|:..:|:.||.||
Human   356 KPYQCDICGKVFRQNSNLVNHQRIHTGEKPYKCNICGKSFSQSSNLATHQTVHSGNKPYKCDECG 420

  Fly   368 STFQRKKALRVHKLLHSEQRKYACKLCGKTFAQSGGLNAHMRSH 411
            .||:|..:|..|:::|:.::.|.|.:|.|.|:|...|..|.|||
Human   421 KTFKRSSSLTTHQIIHTGEKPYTCDVCDKVFSQRSQLARHQRSH 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	COG5236	<222..>313	CDD:227561	44/119 (37%)
		C2H2 Zn finger	224..246	CDD:275368	10/47 (21%)
		C2H2 Zn finger	251..271	CDD:275368	9/19 (47%)
		zf-H2C2_2	263..288	CDD:463886	12/24 (50%)
		C2H2 Zn finger	279..327	CDD:275368	19/47 (40%)
		zf-H2C2_2	320..342	CDD:463886	13/21 (62%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	9/19 (47%)
		zf-C2H2	389..411	CDD:395048	9/21 (43%)
		C2H2 Zn finger	391..411	CDD:275368	8/19 (42%)
ZNF836	NP_001096127.1	KRAB	7..48	CDD:460171
		SFP1	<215..297	CDD:227516	20/103 (19%)
		C2H2 Zn finger	220..240	CDD:275368	6/19 (32%)
		C2H2 Zn finger	248..268	CDD:275368	3/19 (16%)
		COG5048	272..648	CDD:227381	79/193 (41%)
		C2H2 Zn finger	276..296	CDD:275368	7/19 (37%)
		C2H2 Zn finger	304..324	CDD:275368	9/19 (47%)
		C2H2 Zn finger	332..352	CDD:275368	8/19 (42%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
		C2H2 Zn finger	388..408	CDD:275368	7/19 (37%)
		C2H2 Zn finger	416..436	CDD:275368	9/19 (47%)
		C2H2 Zn finger	444..464	CDD:275368	8/19 (42%)
		C2H2 Zn finger	472..492	CDD:275368
		COG5048	496..904	CDD:227381
		C2H2 Zn finger	500..520	CDD:275368
		C2H2 Zn finger	528..548	CDD:275368
		C2H2 Zn finger	556..576	CDD:275368
		C2H2 Zn finger	584..604	CDD:275368
		C2H2 Zn finger	612..632	CDD:275368
		C2H2 Zn finger	640..660	CDD:275368
		C2H2 Zn finger	668..688	CDD:275368
		C2H2 Zn finger	696..714	CDD:275370
		C2H2 Zn finger	724..744	CDD:275368
		C2H2 Zn finger	752..772	CDD:275368
		C2H2 Zn finger	780..800	CDD:275368
		C2H2 Zn finger	808..828	CDD:275368
		C2H2 Zn finger	836..856	CDD:275368
		C2H2 Zn finger	864..884	CDD:275368
		C2H2 Zn finger	892..912	CDD:275368