Protein Alignment CG18262 and Gli3

DIOPT Version :10

• Sequence 1: NP_572453.1
• Gene: CG18262 / 31745
• FlyBaseID: FBgn0030012
• Length: 469
• Species: Drosophila melanogaster
• Sequence 2: NP_536330.2
• Gene: Gli3 / 140588
• RGDID: 620272
• Length: 1582
• Species: Rattus norvegicus
• Alignment Length: 338
• Identity: 79/338 - (23%)
• Similarity: 133/338 - (39%)
• Gaps: 93/338 - (27%)

  Fly   154 GESDDDDTKDSNDTKDMLFQCDQCDRAYNTKRSLQSHRRL-------KHSEANGGSLDKSASERN 211
            |.|:...:|.::::.    .....|..:|.:..::....|       :..:..|.:|.|...:::
  Rat   408 GPSESSQSKPTSESA----VSSTGDPMHNKRSKIKPDEDLPSPGSRGQQEQPEGTTLVKEEGDKD 468

  Fly   212 SKKRKGPPKVYK--CNEEACNQTFRTERDLRGH---------------RWKHTGIFCDICGKPFT 259
            ..|:: |..:|:  |:.|.|.:.|.|:..|..|               ||    :.|....|||.
  Rat   469 ESKQE-PEVIYETNCHWEGCTREFDTQDQLVHHINNDHIHGEKKEFVCRW----LDCSREQKPFK 528

  Fly   260 QSGNMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHM 324
            ....::.|.:||:|.|||||     ||                     |.|.:.......|..|:
  Rat   529 AQYMLVVHMRRHTGEKPHKC-----TF---------------------EGCTKAYSRLENLKTHL 567

  Fly   325 RRHTGERPAKC--EVCGKAFYSFHDLNVHA-VSHTNLRPFVCDVCGST--FQRKKALRVH-KLLH 383
            |.||||:|..|  |.|.|||.:..|...|. .:|:|.:|:||.:.|.|  :....:||.| |.:|
  Rat   568 RSHTGEKPYVCEHEGCNKAFSNASDRAKHQNRTHSNEKPYVCKIPGCTKRYTDPSSLRKHVKTVH 632

  Fly   384 SEQRKYACKLCGKTFAQSGGLN----------AHMRSHDPAR-VKGAV---KPLPQSVT------ 428
            ..:.....|       |.|.::          :|.:|..|.| .:||.   |.|..:.:
  Rat   633 GPEAHVTKK-------QRGDMHPRPPPPRDSGSHSQSRSPGRPTQGAFGEQKELSNTTSKREECL 690

  Fly   429 -IEVIEGKSPPTT 440
             ::.::.:.|.|:
  Rat   691 QVKTVKAEKPMTS 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	COG5236	<222..>313	CDD:227561	27/107 (25%)
		C2H2 Zn finger	224..246	CDD:275368	9/36 (25%)
		C2H2 Zn finger	251..271	CDD:275368	5/19 (26%)
		zf-H2C2_2	263..288	CDD:463886	11/24 (46%)
		C2H2 Zn finger	279..327	CDD:275368	8/47 (17%)
		zf-H2C2_2	320..342	CDD:463886	12/23 (52%)
		C2H2 Zn finger	335..355	CDD:275368	8/22 (36%)
		C2H2 Zn finger	363..383	CDD:275368	7/22 (32%)
		zf-C2H2	389..411	CDD:395048	4/31 (13%)
		C2H2 Zn finger	391..411	CDD:275368	4/29 (14%)
Gli3	NP_536330.2	SFP1	<542..632	CDD:227516	37/115 (32%)
		C2H2 Zn finger	548..570	CDD:275368	8/47 (17%)
		C2H2 Zn finger	578..601	CDD:275368	8/22 (36%)
		C2H2 Zn finger	609..630	CDD:275368	6/20 (30%)