DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG18262 and si:dkey-122c11.8

DIOPT Version :9

Sequence 1:	NP_572453.1	Gene:	CG18262 / 31745	FlyBaseID:	FBgn0030012	Length:	469	Species:	Drosophila melanogaster
Sequence 2:	XP_017211097.1	Gene:	si:dkey-122c11.8 / 108183696	ZFINID:	ZDB-GENE-110913-23	Length:	358	Species:	Danio rerio

Alignment Length:	344	Identity:	101/344 - (29%)
Similarity:	144/344 - (41%)	Gaps:	76/344 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 KEASPDLEEEEEEKEEGSKRQHYQRAAAMKNTLVETREDLLDIELDWTGGEQSE----HNETHEE 151
            ||.|.|::.||                    |....:|||         .||::    ..:||::
Zfish     5 KEESEDVKIEE--------------------TFTVKQEDL---------QEQTDLMLLKEKTHQQ 40

  Fly   152 EEGESDDDD-TKDSND--TKDML-------------FQCDQCDRAYNTKRSLQSHRRLKHSEANG 200
            .|.|....| |.|...  ||..|             |.|.||.::::.|..|..|.| .|:.
Zfish    41 NEMEEKQQDMTTDEKPTLTKKTLSRGRPRKSKPRCNFSCKQCGKSFSQKPKLDVHIR-DHTR--- 101

  Fly   201 GSLDKSASERNSKKRKGPPKVYKCNEEACNQTFRTERDLRGHRWKHTG---IFCDICGKPFTQSG 262
                              .|.|.|.:  |.::|...|:|..|...|||   ..|..|||.|.::|
Zfish   102 ------------------EKAYTCKQ--CGKSFYNTRNLTVHMRIHTGERPYTCQQCGKSFHKTG 146

  Fly   263 NMMRHRQRHSGIKPHKCPECDATFYTQKELSSHSICHTGRMPCICEVCGRPCRDRGVLTAHMRRH 327
            |:..|.:.|:|.:|:.|.:|..:|.|...|:.|...|||..|..|..||:.......|..|||.|
Zfish   147 NLTVHLRIHTGERPYTCQQCGKSFQTTGNLTVHMRIHTGEKPYSCPQCGKSYSQNSNLEVHMRTH 211

  Fly   328 TGERPAKCEVCGKAFYSFHDLNVHAVSHTNLRPFVCDVCGSTFQRKKALRVHKLLHSEQRKYACK 392
            .|.|...|..|||.|....:|::|...||..:|:.|..||.:|..|..|:.|.::|:.::.:||.
Zfish   212 NGGRTFVCTQCGKRFVKKQNLDLHMRIHTGEKPYTCTECGKSFPYKSTLKHHMIVHTGEKPFACA 276

  Fly   393 LCGKTFAQSGGLNAHMRSH 411
            .|||:|..:..|..||..|
Zfish   277 QCGKSFTCNANLRNHMNGH 295

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG18262	NP_572453.1	C2H2 Zn finger	224..246	CDD:275368	6/21 (29%)
		C2H2 Zn finger	251..271	CDD:275368	8/19 (42%)
		COG5048	<256..415	CDD:227381	56/156 (36%)
		zf-H2C2_2	263..288	CDD:290200	8/24 (33%)
		C2H2 Zn finger	279..327	CDD:275368	17/47 (36%)
		zf-H2C2_2	320..342	CDD:290200	11/21 (52%)
		C2H2 Zn finger	335..355	CDD:275368	7/19 (37%)
		C2H2 Zn finger	363..383	CDD:275368	7/19 (37%)
		zf-C2H2	389..411	CDD:278523	9/21 (43%)
		C2H2 Zn finger	391..411	CDD:275368	8/19 (42%)
si:dkey-122c11.8	XP_017211097.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910