Protein Alignment Gbeta5 and Gnb1

DIOPT Version :10

• Sequence 1: NP_572452.1
• Gene: Gbeta5 / 31744
• FlyBaseID: FBgn0030011
• Length: 358
• Species: Drosophila melanogaster
• Sequence 2: NP_112249.2
• Gene: Gnb1 / 24400
• RGDID: 2718
• Length: 340
• Species: Rattus norvegicus
• Alignment Length: 340
• Identity: 164/340 - (48%)
• Similarity: 244/340 - (71%)
• Gaps: 3/340 - (0%)

  Fly    18 KMASLVREAENLKTKLEEERQKLNDVNLSNIAERLEQIAYVNIKPRKVLKGHQAKVLCTDWSPDK 82
            ::..|.:|||.||.::.:.|:...|..||.|...::.:..:.::.|:.|:||.||:....|..|.
  Rat     3 ELDQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDS 67

  Fly    83 RHIISSSQDGRLIIWDAFTTNKEHAVTMPTTWIMACAYAPSGNFVACGGLDNKVTVYPITSDEEM 147
            |.::|:||||:|||||::||||.||:.:.::|:|.||||||||:||||||||..::|.:.:.|..
  Rat    68 RLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGN 132

  Fly   148 AAKKRTVGTHTSYMSCCIYPNSDQQILTGSGDSTCALWDVESGQLLQSFHGHSGDVMAIDLAPNE 212
            ....|.:..||.|:|||.:.: |.||:|.|||:||||||:|:||...:|.||:||||::.|||:.
  Rat   133 VRVSRELAGHTGYLSCCRFLD-DNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDT 196

  Fly   213 TGNTFVSGSCDRMAFIWDMRSGHVVQSFEGHQSDVNSVKFHPCGDAIATGSDDSSCRLYDMRADR 277
              ..||||:||..|.:||:|.|...|:|.||:||:|::.|.|.|:|.||||||::|||:|:|||:
  Rat   197 --RLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQ 259

  Fly   278 EVAVFAKESIIFGVNSVDFSVSGRLLFAGYNDYTVNLWDTLKSERVCLLYGHENKVSCVQVSPDG 342
            |:..::.::||.|:.||.||.|||||.|||:|:..|:||.||::|..:|.||:|:|||:.|:.||
  Rat   260 ELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDG 324

  Fly   343 TALSTGSWDYTIRVW 357
            .|::|||||..:::|
  Rat   325 MAVATGSWDSFLKIW 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gbeta5	NP_572452.1	WD40	62..358	CDD:238121	153/296 (52%)
		WD40 repeat	73..110	CDD:293791	19/36 (53%)
		WD40 repeat	116..156	CDD:293791	20/39 (51%)
		WD40 repeat	161..197	CDD:293791	19/35 (54%)
		WD40 repeat	204..241	CDD:293791	16/36 (44%)
		WD40 repeat	247..283	CDD:293791	19/35 (54%)
		WD40 repeat	291..327	CDD:293791	19/35 (54%)
		WD40 repeat	333..357	CDD:293791	12/23 (52%)
Gnb1	NP_112249.2	WD 1. /evidence=ECO:0000250|UniProtKB:P62873	46..94		25/47 (53%)
		WD40	48..340	CDD:238121	153/295 (52%)
		WD40 repeat	58..95	CDD:293791	19/36 (53%)
		WD 2. /evidence=ECO:0000250|UniProtKB:P62873	95..140		21/44 (48%)
		WD40 repeat	101..141	CDD:293791	20/39 (51%)
		WD 3. /evidence=ECO:0000250|UniProtKB:P62873	141..181		22/40 (55%)
		WD40 repeat	146..181	CDD:293791	19/35 (54%)
		WD 4. /evidence=ECO:0000250|UniProtKB:P62873	182..223		21/42 (50%)
		WD40 repeat	188..223	CDD:293791	16/36 (44%)
		WD 5. /evidence=ECO:0000250|UniProtKB:P62873	224..267		23/42 (55%)
		WD40 repeat	229..265	CDD:293791	19/35 (54%)
		WD 6. /evidence=ECO:0000250|UniProtKB:P62873	268..309		22/40 (55%)
		WD40 repeat	273..309	CDD:293791	19/35 (54%)
		WD 7. /evidence=ECO:0000250|UniProtKB:P62873	310..340		16/30 (53%)
		WD40 repeat	315..339	CDD:293791	12/23 (52%)