DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and CMR3

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_015338.1	Gene:	CMR3 / 856123	SGDID:	S000006217	Length:	317	Species:	Saccharomyces cerevisiae

Alignment Length:	182	Identity:	45/182 - (24%)
Similarity:	68/182 - (37%)	Gaps:	47/182 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 DEETIDTMWQPDHDSSSASVNEGCALEALLGVENPQDYQPDEDGEEHQSVFKKQRQPKDYNCPHC 206
            |:|.|....:|:..:.|.:.:...|||  |..:.|:...|.
Yeast   171 DKEPITIASEPNFTAISMASHPNAALE--LCHDRPKSVPPG------------------------ 209

  Fly   207 DRRY----TTQKYLNTHLKMSHPFPQAFKCVDCKATFD---VDRALAQHR-RKEHTEFACQLCDK 263
               |    |.|:..|...|..   |.|  .::..|||.   .|..::..: ||:     |.:|.|
Yeast   210 ---YGVLPTMQEASNGRTKSE---PGA--VLNGSATFSDWKTDTRISSTKLRKQ-----CPVCGK 261

  Fly   264 VFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYV 315
            :.....:|..|...|:|...|||..|.|.|||..:.|:..|.:.|..:||.|
Yeast   262 ICSRPSTLKTHYLIHTGDTPFKCTWEGCTKSFNVKSNMLRHLKSHERKRNKV 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	6/24 (25%)
		COG5048	<258..416	CDD:227381	21/58 (36%)
		C2H2 Zn finger	258..278	CDD:275368	5/19 (26%)
		C2H2 Zn finger	289..308	CDD:275368	7/18 (39%)
		C2H2 Zn finger	316..336	CDD:275368	45/182 (25%)
		zf-H2C2_2	328..353	CDD:290200
		C2H2 Zn finger	344..364	CDD:275368
		zf-H2C2_2	357..381	CDD:290200
		C2H2 Zn finger	372..392	CDD:275368
		C2H2 Zn finger	400..420	CDD:275368
CMR3	NP_015338.1	COG5048	17..316	CDD:227381	45/182 (25%)
		C2H2 Zn finger	256..276	CDD:275370	5/19 (26%)
		C2H2 Zn finger	284..306	CDD:275370	8/21 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	54	1.000	Inparanoid score	I1809
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.050