Protein Alignment CG10959 and ZBTB17

DIOPT Version :10

• Sequence 1: NP_572451.1
• Gene: CG10959 / 31743
• FlyBaseID: FBgn0030010
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_001274532.1
• Gene: ZBTB17 / 7709
• HGNCID: 12936
• Length: 810
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 115/428 - (26%)
• Similarity: 177/428 - (41%)
• Gaps: 96/428 - (22%)

  Fly    63 DKQGRPLTKTVTGLGRLAREEQEFQGVSA--------------EPLAVDSFKKEYLPNEDVLSEE 113
            ::.||   .|..|..|..:||:..|..||              ||..|: .|.:  |...:.:.|
Human   151 EQAGR---STPIGPSRDLKEERGGQAQSAASGAEQTEKADAPREPPPVE-LKPD--PTSGMAAAE 209

  Fly   114 ------EDAEQELGLEQDEGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASV-NEGCALEALL 171
                  |.:|||:.:|     |.|   .|.::..::|.     |.:..:..|.| .||..||
Human   210 AEAALSESSEQEMEVE-----PAR---KGEEEQKEQEE-----QEEEGAGPAEVKEEGSQLE--- 258

  Fly   172 GVENPQDYQPDE-----DGEE--------HQSVFKKQRQPKDY-----NCPHCDRRYTTQKYLNT 218
            ..|.|::.:.:|     .|:|        ....:..:.:.|.|     .|..|.:.:|.......
Human   259 NGEAPEENENEESAGTDSGQELGSEARGLRSGTYGDRTESKAYGSVIHKCEDCGKEFTHTGNFKR 323

  Fly   219 HLKMSHPFPQAFKCVDCKATFDVDRALAQHRRKEHT---EFACQLCDKVFKSSRSLLRHVQGHSG 280
            |::: |...:.|.|.:|...|. |.|..:...|.|:   .:.|:.|.|.::....|..|.:.|||
Human   324 HIRI-HTGEKPFSCRECSKAFS-DPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSG 386

  Fly   281 ARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCG-------YRSRYREA---------- 328
            ...::|  |:|||.|....||..|:.|||.|:.|.|:.||       .:.|:.|.
Human   387 EARYRC--EDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHLETHDTDKEHKCP 449

  Fly   329 -----------LIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRP 382
                       |..|.:.|..:.|.:|:.|.::|.:...|..|..:||.||||.|..|...|:.|
Human   450 HCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADP 514

  Fly   383 KALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMRAH 420
            .||..|..:|.|.|..:|.:||.|:.||:.|.||:|.|
Human   515 GALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQH 552

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	6/20 (30%)
		COG5048	<258..416	CDD:227381	59/185 (32%)
		C2H2 Zn finger	258..278	CDD:275368	5/19 (26%)
		C2H2 Zn finger	289..308	CDD:275368	8/18 (44%)
		C2H2 Zn finger	316..336	CDD:275368	7/47 (15%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		C2H2 Zn finger	372..392	CDD:275368	7/19 (37%)
		C2H2 Zn finger	400..420	CDD:275368	10/19 (53%)
ZBTB17	NP_001274532.1	BTB_POZ_ZBTB17_MIZ1	2..113	CDD:349515
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..295		37/165 (22%)
		Interaction with MYC	269..308		5/38 (13%)
		COG5048	306..637	CDD:227381	76/251 (30%)
		C2H2 Zn finger	308..328	CDD:275368	4/20 (20%)
		C2H2 Zn finger	336..356	CDD:275368	6/20 (30%)
		C2H2 Zn finger	364..384	CDD:275368	5/19 (26%)
		C2H2 Zn finger	392..412	CDD:275368	9/21 (43%)
		C2H2 Zn finger	420..440	CDD:275368	5/19 (26%)
		C2H2 Zn finger	448..468	CDD:275368	2/19 (11%)
		C2H2 Zn finger	476..496	CDD:275368	5/19 (26%)
		C2H2 Zn finger	504..524	CDD:275368	7/19 (37%)
		C2H2 Zn finger	532..552	CDD:275368	10/19 (53%)
		C2H2 Zn finger	560..580	CDD:275368
		C2H2 Zn finger	588..608	CDD:275368
		C2H2 Zn finger	616..635	CDD:275370
		C2H2 Zn finger	726..746	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	786..810