DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and Zbtb43

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001342539.1	Gene:	Zbtb43 / 71834	MGIID:	1919084	Length:	504	Species:	Mus musculus

Alignment Length:	355	Identity:	76/355 - (21%)
Similarity:	117/355 - (32%)	Gaps:	122/355 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 EGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASVNEGCALEALLGVENPQDY---QPDEDGEE 187
            ||||..:.     |.::..:       ||.|.|:|...|......||.....|:   |...|||.
Mouse   161 EGNPTVLC-----QKLNHGS-------DHQSPSSSNYNGLVESFELGSGGHTDFPKAQELRDGEN 213

  Fly   188 HQ---------SVFKKQRQPKDYNCPHCDR--------------------RYTTQKY----LNTH 219
            .:         .|.:.:..|.:.:..| ||                    .||...|    :..|
Mouse   214 EEESTKDELSSQVTEHEYLPSNSSTEH-DRLSTEMASQDGEEGTNDSTEFHYTRPLYSKPSIMAH 277

  Fly   220 LKMSHPFP----QAFKCVDCKATFD-------VDRALAQH--------------RRKEHTEFACQ 259
            .:..|..|    ||:..:|..|.:|       |:.....|              .:|...||..|
Mouse   278 RRWIHVKPERLEQAWDGMDVHAAYDEHQVTESVNTMQTDHSAQPSGAEEEFQIVEKKVEVEFDEQ 342

  Fly   260 LCDKVF-----------------KSSRSLLRHVQ----------------------GHSG----A 281
            .....:                 |...:|:.|.|                      .|.|    .
Mouse   343 AEGSSYDEQVDFYGSSMEEFSGEKLGGNLIGHKQEAALAAGYSENIEMAMGIKEEASHLGFSATD 407

  Fly   282 RTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQT 346
            :.:.|:   |||||.::.....|..:|...|.|.|.:||.:.:.:..|:.|.:.|||.||::|..
Mouse   408 KLYPCQ---CGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKPYECNI 469

  Fly   347 CARRFASKSLLNEHQAMHSTEKPYKCDKCD 376
            ||:||..:...:.|  :.|..|.|:..|.:
Mouse   470 CAKRFMWRDSFHRH--VTSCTKSYEAAKAE 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	6/41 (15%)
		COG5048	<258..416	CDD:227381	37/162 (23%)
		C2H2 Zn finger	258..278	CDD:275368	5/58 (9%)
		C2H2 Zn finger	289..308	CDD:275368	6/18 (33%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	12/24 (50%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		zf-H2C2_2	357..381	CDD:290200	5/20 (25%)
		C2H2 Zn finger	372..392	CDD:275368	1/5 (20%)
		C2H2 Zn finger	400..420	CDD:275368
Zbtb43	NP_001342539.1	BTB	60..160	CDD:306997
		C2H2 Zn finger	413..431	CDD:275368	6/20 (30%)
		C2H2 Zn finger	439..459	CDD:275368	5/19 (26%)
		zf-H2C2_2	451..474	CDD:316026	10/22 (45%)
		C2H2 Zn finger	467..484	CDD:275368	6/18 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000