DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG10959 and Zbtb7c

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001120847.1	Gene:	Zbtb7c / 679155	RGDID:	1591841	Length:	619	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	64/267 - (23%)
Similarity:	94/267 - (35%)	Gaps:	102/267 - (38%)

- Green bases have known domain annotations that are detailed below.

  Fly   174 ENPQDYQP-----------DEDGEE--------HQSVFKKQRQP-------------KDYNCPHC 206
            |.|.|..|           :|:.||        ..|.|.|...|             .||..
  Rat   272 EQPMDSGPLDLVIKDRKIKEEEKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDYGA--- 333

  Fly   207 DRRYTTQKYLN----THL-KMSHPFPQAFKCVDCKATFDVDRALAQHRR-KEHTEFACQLCDKVF 265
                    |||    ||| .:..|:|                 |.:.|: |......|.:|.||.
  Rat   334 --------YLNFLSATHLGSLFPPWP-----------------LVEERKLKPKASQQCPICHKVI 373

  Fly   266 KSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALI 330
            ..:..|.||::.|:|                              |:.|:|.:|..|...::.|.
  Rat   374 MGAGKLPRHMRTHTG------------------------------EKPYMCSICEVRFTRQDKLK 408

  Fly   331 VHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKHLHLGI 395
            :|.|.||||:|:.|..|..:|.....|..|..:|:..:||:|:.|..:|:|      ..|||..|
  Rat   409 IHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTR------SDHLHRHI 467

  Fly   396 KKFKCKI 402
            |:..|::
  Rat   468 KRQSCRM 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	3/21 (14%)
		COG5048	<258..416	CDD:227381	40/145 (28%)
		C2H2 Zn finger	258..278	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..308	CDD:275368	0/18 (0%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		zf-H2C2_2	328..353	CDD:290200	11/24 (46%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		zf-H2C2_2	357..381	CDD:290200	8/23 (35%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	1/3 (33%)
Zbtb7c	NP_001120847.1	BTB_POZ_ZBTB7C_ZBTB36	9..128	CDD:349637
		C2H2 Zn finger	366..386	CDD:275368	7/19 (37%)
		SFP1	<380..468	CDD:227516	32/123 (26%)
		C2H2 Zn finger	394..414	CDD:275368	6/19 (32%)
		C2H2 Zn finger	422..442	CDD:275368	5/19 (26%)
		C2H2 Zn finger	450..468	CDD:275368	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000