DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and CG17801

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_650660.2	Gene:	CG17801 / 42144	FlyBaseID:	FBgn0038550	Length:	381	Species:	Drosophila melanogaster

Alignment Length:	385	Identity:	90/385 - (23%)
Similarity:	143/385 - (37%)	Gaps:	107/385 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 DVLSEEEDAEQELGLEQDEGNPLRI------------------------MVLGGKQSVDEETIDT 148
            :||::.:|. ..:.|||:|..|..|                        ..|..:..:||:...|
  Fly    29 EVLAKIKDL-TGIWLEQNERQPRHICPSCLNDLNTSIKLKKRIQRVHNEATLRRESGLDEDLEST 92

  Fly   149 M--WQPDHDSSSASVNEGCALEALLGVENPQDYQPDEDGEE--------HQSVFKKQRQPKDYNC 203
            :  .:|:.|||.....|.         .:.::|..|:..||        |:....:...|.|...
  Fly    93 VSDIEPEGDSSDLESEES---------YDSENYPFDKKAEESDIDLNLAHEDRRNEPHNPYDSET 148

  Fly   204 P----HCDRRYTTQKYLN---------------------THLKMSHPFPQAFKCVDCKATFDVDR 243
            |    |.:....|..:.|                     |.|::...:| :.|.|...|....|.
  Fly   149 PLIFKHKNPLIETPSFANENLPNKVDAKSPKKGNFIQIGTDLRLLTTYP-SIKVVKPLALAPEDV 212

  Fly   244 AL-----AQHRRKEHTEFACQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTS 303
            |.     |:...::.....|..|.:|||:..:|..|:..|:|.:.|.|..  |.|.||.::....
  Fly   213 AAENVPPAKRTARKMQSLVCPKCGRVFKTPYNLKTHMVRHTGEKNFPCTF--CDKRFVTKYLARL 275

  Fly   304 HRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAM-HSTE 367
            |.||.                           |.||:||:|..|:..|.:.:..:.|:.: |..:
  Fly   276 HERVR---------------------------HMGEQPFECNFCSATFFTSTAKSSHERIRHIRD 313

  Fly   368 KPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMR--AHKLQAS 425
            ..|:||:|...|:....|..||.||.|:|.|.|.||...:|:.|.|.:|..  ||:.:||
  Fly   314 LRYQCDQCTKRFNTKTCLNKHKFLHSGLKPFDCVICQINFARKATLRSHFDSVAHQKRAS 373

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	5/25 (20%)
		COG5048	<258..416	CDD:227381	47/158 (30%)
		C2H2 Zn finger	258..278	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..308	CDD:275368	6/18 (33%)
		C2H2 Zn finger	316..336	CDD:275368	0/19 (0%)
		zf-H2C2_2	328..353	CDD:290200	8/24 (33%)
		C2H2 Zn finger	344..364	CDD:275368	4/20 (20%)
		zf-H2C2_2	357..381	CDD:290200	7/24 (29%)
		C2H2 Zn finger	372..392	CDD:275368	7/19 (37%)
		C2H2 Zn finger	400..420	CDD:275368	7/21 (33%)
CG17801	NP_650660.2	zf-AD	9..74	CDD:285071	9/45 (20%)
		zf-C2H2	231..252	CDD:278523	7/20 (35%)
		C2H2 Zn finger	232..252	CDD:275368	7/19 (37%)
		zf-H2C2_2	244..269	CDD:290200	9/26 (35%)
		C2H2 Zn finger	260..281	CDD:275368	8/49 (16%)
		C2H2 Zn finger	289..308	CDD:275368	4/18 (22%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..362	CDD:275368	6/15 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030