DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and CG31388

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	308	Identity:	79/308 - (25%)
Similarity:	124/308 - (40%)	Gaps:	50/308 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 EYL-PNEDVLSEEEDAEQELGLEQDEGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASVNEGC 165
            ||: ..:.|.|.:  :..||..:....|....|.|..:...:.|.||     :.|:||:.....|
  Fly   143 EYMNAYQSVASPQ--SSPELSTDSQLSNEHFDMGLSPESEPESEAID-----NRDTSSSHTCSKC 200

  Fly   166 ALEALLGVENP----------QDYQPDEDGEEHQSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHL 220
            .||    .||.          .|..||                ..:.|.|||..:.:...|..|.
  Fly   201 GLE----FENVDELKLHKYHLHDIPPD----------------TKFVCDHCDEGFRSAAALTRHC 245

  Fly   221 KMSHPFPQAFKCVDCKATFDVDRALAQHR----RKEHTEFACQLCDKVFKSSRSLLRHVQGHSGA 281
            .|.: .|....|..||:.|.....|..|:    |...::..|.:|.|...::.:|..|:..|:|.
  Fly   246 NMIN-LPLTHSCTKCKSQFHNHILLETHKQRCLRPPASQHVCHICGKHLTTAFNLKNHLVRHAGT 309

  Fly   282 RTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCEL-CGYRSRYREALIVHRRTH--TGEKPFQ 343
            |..||  :.|..||.....|.||::.|:.||.|:|.. ||...|:..|..:|.|.|  ..::.:|
  Fly   310 RRHKC--DQCSASFYTAAELCSHQKTHTTERPYICRYNCGKTFRFCSARSMHERVHMDASKRIYQ 372

  Fly   344 CQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKHL 391
            |:.|.:.:.:.|....||..|:..:.:.|:.|..:|...|  ::..||
  Fly   373 CEYCPKSYVTPSECRTHQKYHNLTRDHGCEICRISFKTAK--HYRSHL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	7/24 (29%)
		COG5048	<258..416	CDD:227381	41/137 (30%)
		C2H2 Zn finger	258..278	CDD:275368	5/19 (26%)
		C2H2 Zn finger	289..308	CDD:275368	6/18 (33%)
		C2H2 Zn finger	316..336	CDD:275368	7/20 (35%)
		zf-H2C2_2	328..353	CDD:290200	7/26 (27%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		zf-H2C2_2	357..381	CDD:290200	6/23 (26%)
		C2H2 Zn finger	372..392	CDD:275368	6/20 (30%)
		C2H2 Zn finger	400..420	CDD:275368
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071
		C2H2 Zn finger	228..254	CDD:275368	8/26 (31%)
		C2H2 Zn finger	286..306	CDD:275368	5/19 (26%)
		C2H2 Zn finger	314..334	CDD:275368	7/21 (33%)
		C2H2 Zn finger	342..363	CDD:275368	7/20 (35%)
		C2H2 Zn finger	373..393	CDD:275368	5/19 (26%)
		C2H2 Zn finger	401..419	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45439355
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930