DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and ouib

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_649822.2	Gene:	ouib / 41039	FlyBaseID:	FBgn0037618	Length:	312	Species:	Drosophila melanogaster

Alignment Length:	381	Identity:	94/381 - (24%)
Similarity:	152/381 - (39%)	Gaps:	92/381 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LVCLLCDMKHFGFEDFARHIRNVHFDKQGRPLTK---TVTGLGRLAREEQEFQG-----VSAEPL 94
            :||.:|     |.:.......|: ||...|...|   .::|| ||. :..:..|     ..||..
  Fly     4 IVCRVC-----GRQKICEKSLNL-FDLVNRKYLKHLHMISGL-RLV-DLDDVPGFMCLCCQAELR 60

  Fly    95 AVDSFKKEYLPNEDVLSEEEDAEQELGLEQDEGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSA 159
            :..:|:|..:..:         .:.|.:|.|            ..|.||:|.|         :|.
  Fly    61 SALAFRKLCIKTQ---------TKWLTIEDD------------SSSGDEDTND---------NSE 95

  Fly   160 SVNEGCALEALLGVENPQDYQPDEDGEEHQSVFKK--QRQPKDYNCPHCDRRYTTQKYLNTHLKM 222
            ..:|.||.         .|:...::||..:..|:.  :.:|.|             |.||...|
  Fly    96 LESEKCAF---------SDFGKKKEGELVEETFQVLIEEEPMD-------------KTLNRDAK- 137

  Fly   223 SHPFPQA------FKCVDCKATFDVDRALAQHRRKEHTEFACQLCDKVFKSSRSLLRHVQGHSGA 281
                .|.      .|||..:....|...|      :...:.|:||.....|..:..||::.|.|.
  Fly   138 ----AQLREDGIDEKCVPSQKIIKVSTKL------DDQIYICELCGTHATSKPTFQRHMRKHRGE 192

  Fly   282 RTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQT 346
            |.|.|  ::|...|::...|.:|.|||:.|:.:.|..|..|.......::|.||||.::|:.|:.
  Fly   193 RPFGC--KDCDARFLSAGELRAHHRVHTGEQPFACRFCEKRYVSYMGRLIHERTHTNDRPYVCEE 255

  Fly   347 CARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKH--LHL-GIKKFK 399
            |.::|.:..:|..|..:|:.|:.::||.||.:|.|...|..|..  :|| .:||.|
  Fly   256 CGKKFTTAYVLKNHMVIHTGERNFRCDICDRSFQRKAHLVTHTRSMMHLQNVKKQK 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	4/20 (20%)
		COG5048	<258..416	CDD:227381	48/145 (33%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	9/24 (38%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		zf-H2C2_2	357..381	CDD:290200	9/23 (39%)
		C2H2 Zn finger	372..392	CDD:275368	8/21 (38%)
		C2H2 Zn finger	400..420	CDD:275368	94/381 (25%)
ouib	NP_649822.2	zf-AD	5..78	CDD:214871	18/89 (20%)
		COG5048	<158..300	CDD:227381	45/149 (30%)
		C2H2 Zn finger	169..189	CDD:275368	6/19 (32%)
		C2H2 Zn finger	197..217	CDD:275368	6/21 (29%)
		zf-H2C2_2	209..234	CDD:290200	9/24 (38%)
		C2H2 Zn finger	225..245	CDD:275368	5/19 (26%)
		zf-H2C2_2	241..262	CDD:290200	9/20 (45%)
		C2H2 Zn finger	253..273	CDD:275368	5/19 (26%)
		zf-H2C2_2	266..288	CDD:290200	8/21 (38%)
		C2H2 Zn finger	281..299	CDD:275368	8/17 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100