DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and nom

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001262384.1	Gene:	nom / 41038	FlyBaseID:	FBgn0037617	Length:	370	Species:	Drosophila melanogaster

Alignment Length:	463	Identity:	94/463 - (20%)
Similarity:	149/463 - (32%)	Gaps:	172/463 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 VDYVRLHAQQQLRPKCGEIF---YEPEANRFQL---------------VCLLCDMKHFGFEDFAR 55
            ::..|:..:.:|.||..|:|   .:....|.||               ||..|.........|.|
  Fly     3 INVCRVCGRSRLCPKAVELFKPGRQDILRRIQLITGILLQQIPNAPDMVCFCCQTDLQSAMIFRR 67

  Fly    56 H--------IRNVHFDKQGR----------PLTKTVTGLGRLAREEQEFQGVSAEPLAVDSFKKE 102
            .        :..:..||.|.          |.||..|...|..|...        ||.:...
  Fly    68 QCILQQKKWVPLLQSDKVGASEEKKVEPNDPSTKKKTTKRRRGRPRM--------PLEIVDI--- 121

  Fly   103 YLPNEDVLSEEEDAEQELGLEQDEGNPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASVNEGCAL 167
            .:.||...|..|.                   :||.:.  ::.::...:||...|..::.|
  Fly   122 VVTNESKASAGES-------------------VGGDEF--DQPVEISNEPDATDSDVNLEE---- 161

  Fly   168 EALLGVENPQDYQPDEDGEEHQSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKC 232
                 ::     .|||||.|           .|::.|            |..:
  Fly   162 -----ID-----LPDEDGLE-----------SDHDLP------------NVQI------------ 181

  Fly   233 VDCKATFDVDRALAQHRRKEHTEFACQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVN 297
                           |:        |..|..:..:..||:||...|:|.|.:.|  :.|.|:|:.
  Fly   182 ---------------HK--------CDTCGIIKNNKSSLVRHQFEHNGIRPYPC--KECPKTFLV 221

  Fly   298 QHNLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQA 362
            ...|.:|...|                           ||.|.||.|:.|.||:.|.....:|:.
  Fly   222 ASELKAHNLTH---------------------------HTLEPPFACRYCDRRYFSVVGRKKHER 259

  Fly   363 MHSTEKPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHM--RAHKLQAS 425
            :|:.|:|:.||:|..||:|...|..|..:|..::|:.|.:|..:::....|:.|.  ..||..|.
  Fly   260 VHTNERPFVCDQCGKAFTRTCILKAHMAVHQVVRKYSCDVCDRSFSLKKHLATHFISNTHKRNAE 324

  Fly   426 VNATEGAE 433
            . .|..:|
  Fly   325 A-VTSSSE 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	1/20 (5%)
		COG5048	<258..416	CDD:227381	43/157 (27%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		C2H2 Zn finger	289..308	CDD:275368	5/18 (28%)
		C2H2 Zn finger	316..336	CDD:275368	0/19 (0%)
		zf-H2C2_2	328..353	CDD:290200	9/24 (38%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		zf-H2C2_2	357..381	CDD:290200	9/23 (39%)
		C2H2 Zn finger	372..392	CDD:275368	8/19 (42%)
		C2H2 Zn finger	400..420	CDD:275368	4/21 (19%)
nom	NP_001262384.1	zf-AD	5..76	CDD:214871	14/70 (20%)
		C2H2 Zn finger	184..204	CDD:275368	6/19 (32%)
		C2H2 Zn finger	212..261	CDD:275368	18/77 (23%)
		zf-H2C2_2	255..278	CDD:290200	9/22 (41%)
		C2H2 Zn finger	269..289	CDD:275368	8/19 (42%)
		zf-H2C2_2	282..305	CDD:290200	6/22 (27%)
		C2H2 Zn finger	297..313	CDD:275368	3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100