DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and Kah

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_612040.1	Gene:	Kah / 38072	FlyBaseID:	FBgn0035144	Length:	442	Species:	Drosophila melanogaster

Alignment Length:	327	Identity:	80/327 - (24%)
Similarity:	123/327 - (37%)	Gaps:	79/327 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    63 DKQGRPLTKTVTGLGRLAREEQEFQGVSAEPLAVDSFKKEYLPNEDVLSEEEDAEQELGLEQDEG 127
            |:|..|:.:.:..|.:||...     :|..||..|..|.  ||   :.:..:|.......:..:.
  Fly     4 DQQATPIPEELYNLTQLAEVT-----LSVGPLVTDEVKP--LP---LYASSDDDSNYYSHKVFDR 58

  Fly   128 NPLRIMVLGGKQSVDEETIDTMWQPDHDSSSASVNEGCALEALLGVENPQDYQPDEDGEEHQSVF 192
            ..||...:....|.            ..|||:|.:...:.|..||::...... ...||:.:.:.
  Fly    59 RKLRRCTISDSNSC------------ASSSSSSTSSRQSSEDHLGLQGHSSVH-HHHGEQGEILN 110

  Fly   193 KKQRQPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDCKATFDVDRALAQHRRKEHTEFA 257
            .......::.||.|.::|:|...|..| :.:|           ::..|        ::..|
  Fly   111 STSLLEDEHICPECGKKYSTSSNLARH-RQTH-----------RSIMD--------KKARH---- 151

  Fly   258 CQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYR 322
            |..|:||:.|..:...||:.|:..    ||                            |:.||.|
  Fly   152 CPYCEKVYVSMPAYSMHVRTHNQG----CE----------------------------CQFCGKR 184

  Fly   323 SRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYH 387
            ......|..|.|||||||||:|..|.:.||.||.|..|...||..||:.|.:|..||:....||.
  Fly   185 FSRPWLLQGHIRTHTGEKPFKCGVCEKAFADKSNLRAHIQTHSNTKPHTCARCGKAFALKSYLYK 249

  Fly   388 HK 389
            |:
  Fly   250 HE 251

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	1/20 (5%)
		COG5048	<258..416	CDD:227381	44/132 (33%)
		C2H2 Zn finger	258..278	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..308	CDD:275368	0/18 (0%)
		C2H2 Zn finger	316..336	CDD:275368	7/19 (37%)
		zf-H2C2_2	328..353	CDD:290200	14/24 (58%)
		C2H2 Zn finger	344..364	CDD:275368	8/19 (42%)
		zf-H2C2_2	357..381	CDD:290200	10/23 (43%)
		C2H2 Zn finger	372..392	CDD:275368	7/18 (39%)
		C2H2 Zn finger	400..420	CDD:275368
Kah	NP_612040.1	zf-C2H2	119..141	CDD:278523	7/22 (32%)
		C2H2 Zn finger	121..141	CDD:275368	7/20 (35%)
		zf-C2H2	176..198	CDD:278523	9/49 (18%)
		C2H2 Zn finger	178..198	CDD:275368	7/19 (37%)
		zf-H2C2_2	191..214	CDD:290200	13/22 (59%)
		zf-C2H2	204..226	CDD:278523	9/21 (43%)
		C2H2 Zn finger	206..226	CDD:275368	8/19 (42%)
		zf-H2C2_2	218..242	CDD:290200	9/23 (39%)
		C2H2 Zn finger	234..250	CDD:275368	6/15 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100