DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and zgc:165515

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001092697.1	Gene:	zgc:165515 / 323052	ZFINID:	ZDB-GENE-030131-1772	Length:	325	Species:	Danio rerio

Alignment Length:	319	Identity:	77/319 - (24%)
Similarity:	140/319 - (43%)	Gaps:	31/319 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 DVLSEEEDAEQELGLEQDEGNPLRIMVLGGKQSVDEETID--TMWQPDHDSSSASVNEGCALEAL 170
            ::|.||.|   |:.::|::......:||..:::.|::..:  |....:...|.:...|.|.
Zfish     2 ELLKEEID---EITIKQEDVEEQTDLVLPKEENQDQDVSENPTFVIKEEPFSCSQTTEACT---- 59

  Fly   171 LGVENPQDYQPDEDGEEHQSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDC 235
                              |:..:.......:.|..|.:.:..:..|..||: :|...:.|.|..|
Zfish    60 ------------------QTTVQSTETKCSFTCQECGKMFDNKSNLRRHLR-THTVKEDFSCQKC 105

  Fly   236 KATFDVDRALAQH-RRKEHTEFACQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQH 299
            ..:|...::|..| ||...|.::|:.|.::|.:...|..|::.||......|.|  |.:.|..:.
Zfish   106 NTSFTNQKSLDAHSRRYRCTIYSCKRCGRIFPARGGLEVHMRFHSAPLGLSCYH--CERGFKLES 168

  Fly   300 NLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMH 364
            ....|.|||..:..:.|:||..:.:.......|.|.||||:||.|..|...|..|:.|..|..:|
Zfish   169 TYKRHMRVHFIDGCFTCQLCERKCQSLNVFQEHMRIHTGERPFSCDYCKVGFTGKAGLKNHIKVH 233

  Fly   365 STEKPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMRAHKLQ 423
            ..:|.:.|.:|..:|::...|..|.:.|...:.|||::||..::.....:.||:.|:::
Zfish   234 HEDKAFICKRCGKSFAQNAHLKIHMNSHAKKRTFKCQVCGKDFSSENVFNCHMKCHRIE 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	7/21 (33%)
		COG5048	<258..416	CDD:227381	45/157 (29%)
		C2H2 Zn finger	258..278	CDD:275368	5/19 (26%)
		C2H2 Zn finger	289..308	CDD:275368	4/18 (22%)
		C2H2 Zn finger	316..336	CDD:275368	5/19 (26%)
		zf-H2C2_2	328..353	CDD:290200	11/24 (46%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		zf-H2C2_2	357..381	CDD:290200	7/23 (30%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	5/19 (26%)
zgc:165515	NP_001092697.1	zf-C2H2	72..94	CDD:278523	5/22 (23%)
		C2H2 Zn finger	74..94	CDD:275368	5/20 (25%)
		C2H2 Zn finger	102..120	CDD:275368	5/17 (29%)
		C2H2 Zn finger	129..149	CDD:275368	5/19 (26%)
		C2H2 Zn finger	185..205	CDD:275368	5/19 (26%)
		C2H2 Zn finger	213..233	CDD:275368	6/19 (32%)
		C2H2 Zn finger	241..261	CDD:275368	5/19 (26%)
		C2H2 Zn finger	269..289	CDD:275368	5/19 (26%)
		C2H2 Zn finger	297..317	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	0	0.000