DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10959 and ZBTB48

DIOPT Version :9

Sequence 1:NP_572451.1 Gene:CG10959 / 31743 FlyBaseID:FBgn0030010 Length:443 Species:Drosophila melanogaster
Sequence 2:NP_001265576.1 Gene:ZBTB48 / 3104 HGNCID:4930 Length:688 Species:Homo sapiens


Alignment Length:266 Identity:82/266 - (30%)
Similarity:111/266 - (41%) Gaps:33/266 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly   187 EHQSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDCKATFDVDRALAQHRRK 251
            ||::.....|..:.:.|..|...:..:..|..|: :||.....:||..|...|...:.|..|..|
Human   336 EHEARNCMNRSEQVFTCSVCQETFRRRMELRVHM-VSHTGEMPYKCSSCSQQFMQKKDLQSHMIK 399

  Fly   252 EH---TEFACQLCDKVFKSSRSL-LRHVQGHSGARTFKCE-------------------HEN--- 290
            .|   ...||..|.|.|.|...| |.....|.|.:.|.||                   |.|   
Human   400 LHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHIKAKHRNERP 464

  Fly   291 -----CGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARR 350
                 |..:|..:.||..|.|.|:.|:.:.|.|||...|.:.:|..|.||||||:||.|:.|.:|
Human   465 HVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNRTHTGERPFSCEFCEQR 529

  Fly   351 FASKSLLNEHQA-MHSTEKPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLS 414
            |..|..|..|.| .|...:|:.|..|...|...:.|..|...|.|::||:|..||..:.:.|.|.
Human   530 FTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRRHKGVRKFECTECGYKFTRQAHLR 594

  Fly   415 AHMRAH 420
            .||..|
Human   595 RHMEIH 600

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10959NP_572451.1 C2H2 Zn finger 232..253 CDD:275368 6/20 (30%)
COG5048 <258..416 CDD:227381 61/186 (33%)
C2H2 Zn finger 258..278 CDD:275368 7/20 (35%)
C2H2 Zn finger 289..308 CDD:275368 7/26 (27%)
C2H2 Zn finger 316..336 CDD:275368 8/19 (42%)
zf-H2C2_2 328..353 CDD:290200 14/24 (58%)
C2H2 Zn finger 344..364 CDD:275368 8/20 (40%)
zf-H2C2_2 357..381 CDD:290200 8/24 (33%)
C2H2 Zn finger 372..392 CDD:275368 5/19 (26%)
C2H2 Zn finger 400..420 CDD:275368 7/19 (37%)
ZBTB48NP_001265576.1 BTB 16..119 CDD:306997
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 119..140
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..192
C2H2 Zn finger 293..313 CDD:275368
zf-H2C2_2 305..328 CDD:316026
C2H2 Zn finger 321..372 CDD:275368 7/36 (19%)
SFP1 <374..459 CDD:227516 21/84 (25%)
C2H2 Zn finger 380..401 CDD:275368 6/20 (30%)
C2H2 Zn finger 409..425 CDD:275370 6/15 (40%)
C2H2 Zn finger 438..459 CDD:275368 2/20 (10%)
COG5048 <464..612 CDD:227381 50/137 (36%)
C2H2 Zn finger 467..487 CDD:275368 6/19 (32%)
C2H2 Zn finger 495..515 CDD:275368 8/19 (42%)
C2H2 Zn finger 523..540 CDD:275368 6/16 (38%)
C2H2 Zn finger 555..572 CDD:275368 4/16 (25%)
C2H2 Zn finger 580..600 CDD:275368 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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