DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10959 and ZBTB20

DIOPT Version :9

Sequence 1:NP_572451.1 Gene:CG10959 / 31743 FlyBaseID:FBgn0030010 Length:443 Species:Drosophila melanogaster
Sequence 2:NP_001157814.1 Gene:ZBTB20 / 26137 HGNCID:13503 Length:741 Species:Homo sapiens


Alignment Length:505 Identity:112/505 - (22%)
Similarity:171/505 - (33%) Gaps:154/505 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly    13 RLH--AQQQLR-----PKCGEIFYEPEANRFQLVCLLCDMKHFGFEDFARHIRNVH--------F 62
            |:|  :||..|     |:......:|...|.|.:                 :.|:|        :
Human   290 RIHERSQQMERYLSTTPETTHCRKQPRPVRIQTL-----------------VGNIHIKQEMEDDY 337

  Fly    63 DKQGRPLTKTVTGLGRLAREE-----QEFQGVSAEP--------------LAVDSFKKEYLPNED 108
            |..|:   :.|..|.|...||     .:.:|..:||              ...||.::::.|...
Human   338 DYYGQ---QRVQILERNESEECTEDTDQAEGTESEPKGESFDSGVSSSIGTEPDSVEQQFGPGAA 399

  Fly   109 VLSEEEDAEQELGLEQD-EGNPLRIMVLGGKQSVD-------EETIDTMWQPDHDSSSASVNEGC 165
            ..|:.|..:.|...|.. ||.|....:..|..|.:       :.|:.|:    .:||..||.:..
Human   400 RDSQAEPTQPEQAAEAPAEGGPQTNQLETGASSPERSNEVEMDSTVITV----SNSSDKSVLQQP 460

  Fly   166 ALEALLGVENP--QDYQPDEDGEEHQSVFKKQRQPKDYNC----------PHCDRRYTTQKYLNT 218
            ::...:|...|  |.|.     .:.:::....|.|.....          .:....:|||.    
Human   461 SVNTSIGQPLPSTQLYL-----RQTETLTSNLRMPLTLTSNTQVIGTAGNTYLPALFTTQP---- 516

  Fly   219 HLKMSHPFPQAFKCVDCKATFDVDRALAQHRRKEHTEFACQLCDKVFKSSRSL------------ 271
              ..|.|.|..|             :|.|....:.|:|       |..|...|            
Human   517 --AGSGPKPFLF-------------SLPQPLAGQQTQF-------VTVSQPGLSTFTAQLPAPQP 559

  Fly   272 LRHVQGHSGA------RTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALI 330
            |....|||.|      :.::|  ..|.|:|..:.|...|..||:.|:.:.|.:|......::.||
Human   560 LASSAGHSTASGQGEKKPYEC--TLCNKTFTAKQNYVKHMFVHTGEKPHQCSICWRSFSLKDYLI 622

  Fly   331 VHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKHLHL-- 393
            .|..||||.:.:||..|.:||..||.||.|..:|..||.|:|..|...||....|..|..||.  
Human   623 KHMVTHTGVRAYQCSICNKRFTQKSSLNVHMRLHRGEKSYECYICKKKFSHKTLLERHVALHSAS 687

  Fly   394 -----------------GI------KKFKCKICGNAYAQAAGLSAHMRAH 420
                             |:      ..:.|.:|...:.|....:.|||.|
Human   688 NGTPPAGTPPGARAGPPGVVACTEGTTYVCSVCPAKFDQIEQFNDHMRMH 737

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10959NP_572451.1 C2H2 Zn finger 232..253 CDD:275368 2/20 (10%)
COG5048 <258..416 CDD:227381 52/200 (26%)
C2H2 Zn finger 258..278 CDD:275368 4/31 (13%)
C2H2 Zn finger 289..308 CDD:275368 5/18 (28%)
C2H2 Zn finger 316..336 CDD:275368 5/19 (26%)
zf-H2C2_2 328..353 CDD:290200 12/24 (50%)
C2H2 Zn finger 344..364 CDD:275368 9/19 (47%)
zf-H2C2_2 357..381 CDD:290200 10/23 (43%)
C2H2 Zn finger 372..392 CDD:275368 6/19 (32%)
C2H2 Zn finger 400..420 CDD:275368 6/19 (32%)
ZBTB20NP_001157814.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..32
BTB_POZ_ZBTB20_DPZF 79..195 CDD:349517
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 203..235
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 350..440 18/89 (20%)
PHA03169 <352..>442 CDD:223003 17/89 (19%)
Med15 <378..>571 CDD:312941 43/227 (19%)
zf-C2H2 578..600 CDD:395048 6/23 (26%)
C2H2 Zn finger 580..600 CDD:275368 6/21 (29%)
SUF4-like 608..>657 CDD:411020 19/48 (40%)
C2H2 Zn finger 608..629 CDD:411020 6/20 (30%)
C2H2 Zn finger 608..628 CDD:275368 5/19 (26%)
zf-C2H2 634..656 CDD:395048 10/21 (48%)
C2H2 Zn finger 636..656 CDD:411020 9/19 (47%)
C2H2 Zn finger 636..656 CDD:275368 9/19 (47%)
zf-H2C2_2 648..673 CDD:404364 10/24 (42%)
C2H2 Zn finger 664..684 CDD:275368 6/19 (32%)
C2H2 Zn finger 717..737 CDD:275368 6/19 (32%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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