Protein Alignment CG10959 and Zfp729a

DIOPT Version :10

• Sequence 1: NP_572451.1
• Gene: CG10959 / 31743
• FlyBaseID: FBgn0030010
• Length: 443
• Species: Drosophila melanogaster
• Sequence 2: NP_001388795.1
• Gene: Zfp729a / 212281
• MGIID: 3036250
• Length: 994
• Species: Mus musculus
• Alignment Length: 446
• Identity: 127/446 - (28%)
• Similarity: 190/446 - (42%)
• Gaps: 85/446 - (19%)

  Fly    24 CGEIFYEPE--ANR---------FQLVCLLCDMKHFGFEDFARHIRNVHFDKQG---RPLTKTVT 74
            ||:.||.|.  :|.         ||  |.:|. |.|.|.......:.:|..::.   :...|...
Mouse   481 CGKAFYYPSRLSNHKKIHTGEKPFQ--CEVCG-KAFCFPSSLSKHKRIHTGEKPYKCKECGKAFR 542

  Fly    75 GLGRLAREEQEFQGVSAEPLAVDSFKKEY-----LPNEDVLSEEEDAEQELGLEQDEGNPLRIMV 134
            .|..|::.::...|  .:|...:...|.:     |....::..||             .|.:..|
Mouse   543 SLSSLSKHKRIHTG--EKPYKCEECGKAFHYPSLLSKHKIIHTEE-------------KPYKCDV 592

  Fly   135 LGGKQSVDEETIDTMWQPDHDSSSASVN------------EGC----ALEALLGV-------ENP 176
            .|              |..|..|..|.:            |.|    .:..||..       |||
Mouse   593 CG--------------QAFHVPSKLSHHKIIHTGEKPYKCEVCGKAFCIPLLLSKHKRVHTGENP 643

  Fly   177 QDYQPDEDGEEHQSVFKKQR----QPKDYNCPHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDCKA 237
            .:.|.......:.|...|.:    :.|.|.|..|.:.:.....|..| |..|...:.:||.||..
Mouse   644 YNSQVCSKAFVYPSKLSKHKKVRTKEKPYKCEVCGKAFRFPSLLLIH-KGMHTGEKPYKCEDCGK 707

  Fly   238 TFDVDRALAQHRRKEHT---EFACQLCDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQH 299
            .|.....|::|:| .||   .:.|::|.|.|..|.||.:|...|:|.:.:||  |.|||:|....
Mouse   708 AFHYPSLLSKHKR-IHTGEKPYQCEVCGKDFHVSSSLSKHRIIHTGEKPYKC--EICGKTFRFSS 769

  Fly   300 NLTSHRRVHSEERNYVCELCGYRSRYREALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMH 364
            :|:.|:|.|:.::.|.||.||....:...|..|:.:||||||:.|..|.:.|...|||::|:.:|
Mouse   770 SLSKHKRNHTGKKPYKCEECGKAFHFPSILAKHKISHTGEKPYNCDLCGKAFHYASLLSKHKMIH 834

  Fly   365 STEKPYKCDKCDSAFSRPKALYHHKHLHLGIKKFKCKICGNAYAQAAGLSAHMRAH 420
            :.|||:|||.|..||..|..|.:||.:|.|.|.:||::|||.:..|:.||.|.|.|
Mouse   835 TGEKPHKCDICGKAFHYPSKLSNHKKIHTGEKPYKCEVCGNVFCFASSLSKHKRIH 890

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	7/20 (35%)
		COG5048	<258..416	CDD:227381	66/157 (42%)
		C2H2 Zn finger	258..278	CDD:275368	8/19 (42%)
		C2H2 Zn finger	289..308	CDD:275368	8/18 (44%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		C2H2 Zn finger	344..364	CDD:275368	7/19 (37%)
		C2H2 Zn finger	372..392	CDD:275368	9/19 (47%)
		C2H2 Zn finger	400..420	CDD:275368	9/19 (47%)
Zfp729a	NP_001388795.1	KRAB	36..94	CDD:214630
		C2H2 Zn finger	114..131	CDD:275368
		C2H2 Zn finger	142..162	CDD:275368
		SFP1	<164..233	CDD:227516
		C2H2 Zn finger	170..190	CDD:275368
		C2H2 Zn finger	198..218	CDD:275368
		C2H2 Zn finger	226..246	CDD:275368
		COG5048	250..691	CDD:227381	46/242 (19%)
		C2H2 Zn finger	254..274	CDD:275368
		C2H2 Zn finger	282..302	CDD:275368
		C2H2 Zn finger	310..330	CDD:275368
		C2H2 Zn finger	338..358	CDD:275368
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	394..414	CDD:275368
		C2H2 Zn finger	425..442	CDD:275368
		C2H2 Zn finger	450..470	CDD:275368
		C2H2 Zn finger	478..498	CDD:275368	6/16 (38%)
		C2H2 Zn finger	506..526	CDD:275368	5/20 (25%)
		COG5048	530..972	CDD:227381	113/394 (29%)
		C2H2 Zn finger	534..554	CDD:275368	3/19 (16%)
		C2H2 Zn finger	562..582	CDD:275368	2/19 (11%)
		C2H2 Zn finger	590..610	CDD:275368	6/33 (18%)
		C2H2 Zn finger	618..638	CDD:275368	4/19 (21%)
		C2H2 Zn finger	647..666	CDD:275368	3/18 (17%)
		C2H2 Zn finger	674..694	CDD:275368	5/20 (25%)
		C2H2 Zn finger	702..722	CDD:275368	7/20 (35%)
		C2H2 Zn finger	730..750	CDD:275368	8/19 (42%)
		C2H2 Zn finger	758..778	CDD:275368	9/21 (43%)
		C2H2 Zn finger	786..806	CDD:275368	6/19 (32%)
		C2H2 Zn finger	814..834	CDD:275368	7/19 (37%)
		C2H2 Zn finger	842..862	CDD:275368	9/19 (47%)
		C2H2 Zn finger	870..890	CDD:275368	9/19 (47%)
		C2H2 Zn finger	898..918	CDD:275368
		C2H2 Zn finger	926..946	CDD:275368
		C2H2 Zn finger	954..974	CDD:275368