DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and Zbtb7c

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	XP_036016934.1	Gene:	Zbtb7c / 207259	MGIID:	2443302	Length:	625	Species:	Mus musculus

Alignment Length:	402	Identity:	84/402 - (20%)
Similarity:	129/402 - (32%)	Gaps:	180/402 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   106 NEDVLSEEEDAEQELGLEQDEGNPLRIMVLGGKQSVDEETI---------------DTMWQPDHD 155
            :||...|||:.|:|   |::|.:|        :...|:|.:               |.:.:.|:.
Mouse   154 DEDEDDEEEEEEEE---EEEEDDP--------EDFADQENLPDPQDITCPQSPSKTDHLTEKDYS 207

  Fly   156 SS--------------SASVNEGCALEALL---------------------------------GV 173
            .:              ...|....::|:||                                 |.
Mouse   208 DTPRDFPDSFQPGSPGHLGVIRDFSIESLLRENLYPKANIPDRRPSLSPFAPEFFPHLWPGGFGA 272

  Fly   174 -----ENPQDYQP-----------DEDGEE--------HQSVFKKQRQP-------------KDY 201
                 |.|.|..|           :||.||        ..|.|.|...|             .||
Mouse   273 FAQLPEQPMDSGPLDLVIKNRKIKEEDKEELAPPPPPPFSSDFFKDMFPDLPGGPLGPIKAENDY 337

  Fly   202 NCPHCDRRYTTQKYLN----THL-KMSHPFPQAFKCVDCKATFDVDRALAQHRR-KEHTEFACQL 260
            ..           |||    ||| .:..|:|                 |.:.|: |......|.:
Mouse   338 GA-----------YLNFLSATHLGSLFPPWP-----------------LVEERKLKPKASQQCPI 374

  Fly   261 CDKVFKSSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRY 325
            |.||...:..|.||::.|:|                              |:.|:|.:|..|...
Mouse   375 CHKVIMGAGKLPRHMRTHTG------------------------------EKPYMCSICEVRFTR 409

  Fly   326 REALIVHRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKH 390
            ::.|.:|.|.||||:|:.|..|..:|.....|..|..:|:..:||:|:.|..:|:|      ..|
Mouse   410 QDKLKIHMRKHTGERPYLCIHCNAKFVHNYDLKNHMRIHTGVRPYQCEFCYKSFTR------SDH 468

  Fly   391 LHLGIKKFKCKI 402
            ||..||:..|::
Mouse   469 LHRHIKRQSCRM 480

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	3/21 (14%)
		COG5048	<258..416	CDD:227381	40/145 (28%)
		C2H2 Zn finger	258..278	CDD:275368	7/19 (37%)
		C2H2 Zn finger	289..308	CDD:275368	0/18 (0%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		zf-H2C2_2	328..353	CDD:290200	11/24 (46%)
		C2H2 Zn finger	344..364	CDD:275368	5/19 (26%)
		zf-H2C2_2	357..381	CDD:290200	8/23 (35%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	1/3 (33%)
Zbtb7c	XP_036016934.1	BTB_POZ_ZBTB7C_ZBTB36	15..134	CDD:349637
		C2H2 Zn finger	372..392	CDD:275368	7/19 (37%)
		SFP1	<386..474	CDD:227516	32/123 (26%)
		C2H2 Zn finger	400..420	CDD:275368	6/19 (32%)
		C2H2 Zn finger	428..448	CDD:275368	5/19 (26%)
		C2H2 Zn finger	456..474	CDD:275368	7/23 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000