DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and mtf1

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	XP_002939525.1	Gene:	mtf1 / 100495484	XenbaseID:	XB-GENE-979128	Length:	727	Species:	Xenopus tropicalis

Alignment Length:	342	Identity:	88/342 - (25%)
Similarity:	141/342 - (41%)	Gaps:	97/342 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   105 PNEDVLSEEEDAEQELGLEQDEGNPLRIMVLGGK----QSVDEETIDTMWQPDHDSSSASVNEGC 165
            |:|   :||:|.|.:   |.|:||      :|..    .:.:||.:  :..|:.|:.|
Frog    53 PSE---AEEDDEEDD---EDDDGN------VGTNLPFLDAANEEGL--LLLPEQDAMS------- 96

  Fly   166 ALEALLGVENPQDY-----QPDEDGEEHQSVFKKQRQPKDYNCPHCDRRYTTQKYLNTHLKM--- 222
                       |.|     .||:                                  .||.:
Frog    97 -----------QGYVQHIISPDQ----------------------------------IHLTINPG 116

  Fly   223 SHPFPQAFKCVDCKATFDVDRALAQHRRKEHTEFACQL--CDKVFKSSRSLLRHVQGHSGARTFK 285
            |.|.|:..:    .||..:.....:.::||...:.|..  |.:.:.::.:|..|.:.|.|..||.
Frog   117 STPMPRNIE----GATLTLQSECPETKQKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFV 177

  Fly   286 CEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCG----YRSRYREALIVHRRTHTGEKPFQCQT 346
            |....|||:|:..::|..|.|||::|:.:.|::.|    :.:.||  |..|:|.|||| .|.|.|
Frog   178 CNQSGCGKAFLTSYSLKIHVRVHTKEKPFECDVQGCEKAFNTLYR--LRAHQRLHTGE-TFNCVT 239

  Fly   347 --CARRFASKSLLNEHQAMHSTEKPYKCDK--CDSAFSRPKALYHHKHLHLGIKKFKCKI--CGN 405
              |::.|.:.|.|.:|...|:.|||::||.  |..||:....|..|...|.|.|.|.|..  |..
Frog   240 EGCSKFFTTHSDLRKHIRTHTREKPFRCDHDGCGKAFAASHHLKTHARKHTGEKPFLCTSDGCEK 304

  Fly   406 AYAQAAGLSAHMRAHKL 422
            .::....|.:||:.|.:
Frog   305 TFSTQYSLKSHMKGHDI 321

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	3/20 (15%)
		COG5048	<258..416	CDD:227381	56/169 (33%)
		C2H2 Zn finger	258..278	CDD:275368	4/21 (19%)
		C2H2 Zn finger	289..308	CDD:275368	7/18 (39%)
		C2H2 Zn finger	316..336	CDD:275368	7/23 (30%)
		zf-H2C2_2	328..353	CDD:290200	12/26 (46%)
		C2H2 Zn finger	344..364	CDD:275368	7/21 (33%)
		zf-H2C2_2	357..381	CDD:290200	11/25 (44%)
		C2H2 Zn finger	372..392	CDD:275368	7/21 (33%)
		C2H2 Zn finger	400..420	CDD:275368	5/21 (24%)
mtf1	XP_002939525.1	COG5048	<89..297	CDD:227381	69/266 (26%)
		C2H2 Zn finger	151..170	CDD:275368	3/18 (17%)
		C2H2 Zn finger	178..200	CDD:275368	8/21 (38%)
		C2H2 Zn finger	208..230	CDD:275368	7/23 (30%)
		COG5048	239..>360	CDD:227381	27/83 (33%)
		C2H2 Zn finger	240..259	CDD:275368	5/18 (28%)
		C2H2 Zn finger	267..289	CDD:275368	7/21 (33%)
		C2H2 Zn finger	297..319	CDD:275368	5/21 (24%)
		PHA03247	<404..659	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910