DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10959 and si:ch211-241b2.4

DIOPT Version :9

Sequence 1:	NP_572451.1	Gene:	CG10959 / 31743	FlyBaseID:	FBgn0030010	Length:	443	Species:	Drosophila melanogaster
Sequence 2:	NP_001373223.1	Gene:	si:ch211-241b2.4 / 100150909	ZFINID:	ZDB-GENE-081104-191	Length:	294	Species:	Danio rerio

Alignment Length:	296	Identity:	90/296 - (30%)
Similarity:	140/296 - (47%)	Gaps:	24/296 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   141 VDEETIDTMWQPDHDSSSASVNEGCALEALLGVEN-PQDY-QPDEDGEEHQSVFKKQRQPKDYNC 203
            ::||  |.|  .|.||......|...|..::.||: |..: ..|...:.|..        .::.|
Zfish    14 LEEE--DDM--SDLDSYGKIKEEQQDLLTIIEVEDTPHQFITGDTSSQTHLR--------DEFPC 66

  Fly   204 PHCDRRYTTQKYLNTHLKMSHPFPQAFKCVDCKATFDVDRALAQHRRKEHTE--FACQLCDKVFK 266
            .||.:.::....||.| |.:|...:.|.||.|..:|.......:|.:....|  |||..|.|.|.
Zfish    67 THCGKSFSCTSNLNRH-KKTHSGERPFTCVQCGKSFARRENFYRHNQSHIGEKSFACMQCGKSFV 130

  Fly   267 SSRSLLRHVQGHSGARTFKCEHENCGKSFVNQHNLTSHRRVHSEERNYVCELCGYRSRYREALIV 331
            ...:|.:|::.|||.|.::|  |.|||:|....:|..|..:|::.:.|.|..|.......:.|..
Zfish   131 FVDALKKHMRCHSGDRPYEC--EQCGKTFTLMSSLKRHMIIHTDLKPYACSQCERSFSRLDCLKK 193

  Fly   332 HRRTHTGEKPFQCQTCARRFASKSLLNEHQAMHSTEKPYKCDKCDSAFSRPKALYHHKHLHLGIK 396
            |::|||..:|..|..|...|:|..:|..|..:|:.||||.|.:|..:|::...|..|:.:|.|.|
Zfish   194 HQKTHTDARPHLCLQCGSAFSSADILKRHHRIHTGEKPYSCSECGKSFTQSGHLMQHERVHTGRK 258

  Fly   397 KFKCKICGNAYAQAAGLSAHMRAHKLQASVNATEGA 432
            .:.|.|||.:::.|..|.||::.|     :..|.||
Zfish   259 PYICSICGRSFSTARNLPAHIKKH-----LTMTTGA 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10959	NP_572451.1	C2H2 Zn finger	232..253	CDD:275368	5/20 (25%)
		COG5048	<258..416	CDD:227381	53/157 (34%)
		C2H2 Zn finger	258..278	CDD:275368	6/19 (32%)
		C2H2 Zn finger	289..308	CDD:275368	7/18 (39%)
		C2H2 Zn finger	316..336	CDD:275368	4/19 (21%)
		zf-H2C2_2	328..353	CDD:290200	9/24 (38%)
		C2H2 Zn finger	344..364	CDD:275368	6/19 (32%)
		zf-H2C2_2	357..381	CDD:290200	10/23 (43%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		C2H2 Zn finger	400..420	CDD:275368	8/19 (42%)
si:ch211-241b2.4	NP_001373223.1	COG5048	<43..272	CDD:227381	72/239 (30%)
		C2H2 Zn finger	66..86	CDD:275368	7/20 (35%)
		C2H2 Zn finger	94..114	CDD:275368	5/19 (26%)
		C2H2 Zn finger	122..142	CDD:275368	6/19 (32%)
		C2H2 Zn finger	150..170	CDD:275368	8/21 (38%)
		C2H2 Zn finger	178..198	CDD:275368	4/19 (21%)
		C2H2 Zn finger	206..226	CDD:275368	6/19 (32%)
		C2H2 Zn finger	234..254	CDD:275368	5/19 (26%)
		C2H2 Zn finger	262..282	CDD:275368	8/19 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910