Protein Alignment CG2129 and ZNF160

DIOPT Version :10

• Sequence 1: NP_572449.1
• Gene: CG2129 / 31741
• FlyBaseID: FBgn0030008
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_047295573.1
• Gene: ZNF160 / 90338
• HGNCID: 12948
• Length: 837
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 129/522 - (24%)
• Similarity: 192/522 - (36%)
• Gaps: 141/522 - (27%)

  Fly    14 ANAKCGEIYFQSLHSFRIDCAFCEMKSFVFGDFLLHVQNIHFENGLLKTEATDAG------ANLK 72
            ||: ||:.|         .|..|. |:|.....|...:.||  :|....:.::.|      :||
Human   269 ANS-CGKPY---------KCNECG-KAFTQNSNLTSHRRIH--SGEKPYKCSECGKTFTVRSNL- 319

  Fly    73 QERDREREPNSPVPIVAQV-----NPFAWYEIGG--DHNEDSDDERVVLEKQDEDEDERPGRSII 130
                          .:.||     .|:..:|.|.  .||......|.:...:...:....|::
Human   320 --------------TIHQVIHTGEKPYKCHECGKVFRHNSYLATHRRIHTGEKPYKCNECGKA-- 368

  Fly   131 KWQDHQSLTSESLRQVRALKVDYKEEDSEQEECG----MELDLDSEGR-HSAKIPHSCPHCTKVY 190
             ::.|.:||:..|       :...|:..:..|||    ....|.|..| |:.:.|:.|..|.|.:
Human   369 -FRGHSNLTTHQL-------IHTGEKPFKCNECGKLFTQNSHLISHWRIHTGEKPYKCNECGKAF 425

  Fly   191 QSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAAQEYKCEHCGKIYHGKYSLRQHLKR 255
            ..|..|..|                         ..:.:..:.|||..|||::.....|.:| :|
Human   426 SVRSSLAIH-------------------------QTIHTGEKPYKCNECGKVFRYNSYLGRH-RR 464

  Fly   256 DHDNGE------EGGSAI------------------FTCLECEAQLPRLRLLDEHMVQAHGGA-- 294
            .| .||      |.|.|.                  |.|.||.....:...|..|. :.|.|.
Human   465 VH-TGEKPYKCNECGKAFSMHSNLATHQVIHTGTKPFKCNECSKVFTQNSQLANHR-RIHTGEKP 527

  Fly   295 -ACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNH---------------G 343
             .|..||:.:..|..|..||..|:.|:...|..  |||.|....|:|:|               |
Human   528 YKCNECGKAFSVRSSLTTHQAIHSGEKPYKCIE--CGKSFTQKSHLRSHRGIHSGEKPYKCNECG 590

  Fly   344 K-------------VHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGL 395
            |             |||.:|.:.|..||.:..::.:|..|...||||:|:.|..|.|.|..:|.|
Human   591 KVFAQTSQLARHWRVHTGEKPYKCNDCGRAFSDRSSLTFHQAIHTGEKPYKCHECGKVFRHNSYL 655

  Fly   396 REHMAMHSTERPHVCSVCGATFSRQKGLYHHKFLHADTKQFVCKLCGNAYAQAAGLAGHMRKHRN 460
            ..|..:|:.|:|:.|:.||..||....|..||.:|...|.:.|..||..:.|.:.||.|.|.|..
Human   656 ATHRRIHTGEKPYKCNECGKAFSMHSNLTTHKVIHTGEKPYKCNQCGKVFTQNSHLANHQRTHTG 720

  Fly   461 DE 462
            ::
Human   721 EK 722

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	SFP1	<180..258	CDD:227516	16/77 (21%)
		C2H2 Zn finger	296..316	CDD:275370	7/19 (37%)
		zf-C2H2_8	323..411	CDD:464935	34/115 (30%)
		C2H2 Zn finger	327..346	CDD:275368	9/46 (20%)
		C2H2 Zn finger	354..374	CDD:275368	5/19 (26%)
		SFP1	<376..461	CDD:227516	32/84 (38%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		C2H2 Zn finger	410..430	CDD:275368	8/19 (42%)
		C2H2 Zn finger	438..458	CDD:275368	8/19 (42%)
ZNF160	XP_047295573.1	KRAB	27..87	CDD:214630
		SFP1	<235..351	CDD:227516	23/109 (21%)
		C2H2 Zn finger	278..298	CDD:275368	5/20 (25%)
		zf-H2C2_2	290..314	CDD:463886	5/25 (20%)
		C2H2 Zn finger	306..326	CDD:275368	5/34 (15%)
		C2H2 Zn finger	334..354	CDD:275368	5/19 (26%)
		zf-H2C2_2	346..369	CDD:463886	2/25 (8%)
		C2H2 Zn finger	362..382	CDD:275368	5/29 (17%)
		COG5048	386..829	CDD:227381	99/367 (27%)
		C2H2 Zn finger	390..410	CDD:275368	6/19 (32%)
		C2H2 Zn finger	418..438	CDD:275368	6/44 (14%)
		C2H2 Zn finger	446..466	CDD:275368	7/20 (35%)
		C2H2 Zn finger	474..494	CDD:275368	3/19 (16%)
		C2H2 Zn finger	502..522	CDD:275368	5/20 (25%)
		C2H2 Zn finger	530..550	CDD:275368	7/19 (37%)
		C2H2 Zn finger	558..578	CDD:275368	8/21 (38%)
		C2H2 Zn finger	586..606	CDD:275368	2/19 (11%)
		C2H2 Zn finger	614..634	CDD:275368	5/19 (26%)
		C2H2 Zn finger	642..662	CDD:275368	7/19 (37%)
		C2H2 Zn finger	670..690	CDD:275368	8/19 (42%)
		C2H2 Zn finger	698..718	CDD:275368	8/19 (42%)
		C2H2 Zn finger	726..746	CDD:275368
		C2H2 Zn finger	754..774	CDD:275368
		C2H2 Zn finger	782..802	CDD:275368
		C2H2 Zn finger	810..830	CDD:275368