DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and STP4

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_010235.1	Gene:	STP4 / 851512	SGDID:	S000002206	Length:	490	Species:	Saccharomyces cerevisiae

Alignment Length:	298	Identity:	57/298 - (19%)
Similarity:	97/298 - (32%)	Gaps:	66/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   112 VVLEKQDEDEDERPGRSIIKWQDHQSLTSE-SLRQVRALKVDYK-EEDSEQEECGM--------- 165
            :|.::|.:..:.....|.:. ..|..||:| :.|...:||...| .:..:::||.:
Yeast   227 IVKQQQQQQLNSSSSASALP-SIHSPLTNEHTSRYSSSLKDSAKITKQRKKKECPICHNFYANLS 290

  Fly   166 ---ELDLDSEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPV 227
               ...|..|.|     ||.||.|.:.:.....|.||..|..||... .:.:.::|.....|...
Yeast   291 THKSTHLTPEDR-----PHKCPICQRGFARNNDLIRHKKRHWKDEFM-QIYARESDNNSGADDQD 349

  Fly   228 KSAAQEYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQA-- 290
            .:|                   |.....|.|:..:.       |...:.....:||.::.:::
Yeast   350 DTA-------------------RTSANNDSDDSNDK-------LAASSSSEETKLLKKNQLKSLY 388

  Fly   291 --HGGAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIR------HMRNHGKVHT 347
              .|...|...........|:..|:.:......:.|...|...|..|.:      |.....|...
Yeast   389 KIKGAFKCPYNSTLINLDMEVYPHKSRSLYFEPINCHQTGVFSRCDTFKNHLKALHFEYPPKTKK 453

  Fly   348 EQKNFV---CESCGYSCRNKETLRVHIRSHTGERPFGC 382
            |.:..|   |:.||....|.:   |.:..|.|:   ||
Yeast   454 EDRGVVPGKCKHCGLQFPNVD---VWLNKHVGK---GC 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	3/19 (16%)
		zf-C2H2_8	323..411	CDD:292531	17/69 (25%)
		C2H2 Zn finger	327..346	CDD:275368	5/24 (21%)
		C2H2 Zn finger	354..374	CDD:275368	5/19 (26%)
		zf-H2C2_2	367..389	CDD:290200	5/16 (31%)
		C2H2 Zn finger	382..402	CDD:275368	1/1 (100%)
		zf-H2C2_2	395..419	CDD:290200
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
STP4	NP_010235.1	COG5048	14..442	CDD:227381	44/247 (18%)
		C2H2 Zn finger	279..296	CDD:275368	1/16 (6%)
		C2H2 Zn finger	306..326	CDD:275368	6/19 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100