Protein Alignment CG2129 and ZNF282

DIOPT Version :10

• Sequence 1: NP_572449.1
• Gene: CG2129 / 31741
• FlyBaseID: FBgn0030008
• Length: 465
• Species: Drosophila melanogaster
• Sequence 2: XP_006716214.1
• Gene: ZNF282 / 8427
• HGNCID: 13076
• Length: 672
• Species: Homo sapiens
• Alignment Length: 438
• Identity: 99/438 - (22%)
• Similarity: 158/438 - (36%)
• Gaps: 88/438 - (20%)

  Fly    80 EPNSPVPIVAQVNPFAWY-------------EIGGDHNEDSDDERVVLEKQDE---------DED 122
            :|::||....:..|..|.             |.|.:....:.|....::::|.         :|.
Human   245 KPDAPVQAEPREEPCVWEQRHPEEREIPMDPEAGAEPLVPAQDASSQVKREDTLCVRGQRGLEER 309

  Fly   123 ERPGRSI--------------IKWQDHQSL---------------TSESLRQVRALKVDYKEED- 157
            ..|..||              ||.::||.:               .||||.....:....|:|:
Human   310 AIPTESITVDSPISAQDLLSRIKQEEHQCVWDQQDLADRDIPTDPNSESLISAHDILSWIKQEEQ 374

  Fly   158 ----SEQEECGMELDLDSEGRHSAKIPHSCPHCTKVYQSR-KVLERHIMRQHKDTLSPDVDSEDA 217
                ..::....||.|||....|..:..:.|......|.: :..:..:..|.:....|.:...:.
Human   375 PYPWGPRDSMDGELGLDSGPSDSLLMVKNPPPAPPQPQPQPQPPQPQLQSQPQPQSLPPIAVAEN 439

  Fly   218 DYEPPKDAPVKSAAQEYKCEH-CGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLR 281
            ...||....:....|....|. .|:...|  ..|.......|.|..||.|
Human   440 PGGPPSRGLLDDGFQVLPGERGSGEAPPG--GDRSTGGGGGDGGGGGGGA--------------- 487

  Fly   282 LLDEHMVQAHGG-AACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGKV 345
               |....|.|| .:|...|        |:|..|.| ..|:.|...|.|||.|...:.:..|.:.
Human   488 ---EAGTGAGGGCGSCCPGG--------LRRSLLLH-GARSKPYSCPECGKSFGVRKSLIIHHRS 540

  Fly   346 HTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVC 410
            ||:::.:.|..|..|......|..|..:|.||||:.|..|:|.:.....|:.|..:|:.|||..|
Human   541 HTKERPYECAECEKSFNCHSGLIRHQMTHRGERPYKCSECEKTYSRKEHLQNHQRLHTGERPFQC 605

  Fly   411 SVCGATFSRQKGLYHHKFLHADTKQFVCKLCGNAYAQAAGLAGHMRKH 458
            ::||.:|.|::.|..|:.:|...:.:.|..||.::.....|..|:|.|
Human   606 ALCGKSFIRKQNLLKHQRIHTGERPYTCGECGKSFRYKESLKDHLRVH 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	SFP1	<180..258	CDD:227516	11/79 (14%)
		C2H2 Zn finger	296..316	CDD:275370	5/19 (26%)
		zf-C2H2_8	323..411	CDD:464935	28/87 (32%)
		C2H2 Zn finger	327..346	CDD:275368	6/18 (33%)
		C2H2 Zn finger	354..374	CDD:275368	5/19 (26%)
		SFP1	<376..461	CDD:227516	28/83 (34%)
		C2H2 Zn finger	382..402	CDD:275368	5/19 (26%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368	6/19 (32%)
ZNF282	XP_006716214.1	KRAB	198..260	CDD:214630	4/14 (29%)
		COG5048	<507..652	CDD:227381	45/145 (31%)
		C2H2 Zn finger	521..541	CDD:275368	6/19 (32%)
		C2H2 Zn finger	549..569	CDD:275368	5/19 (26%)
		C2H2 Zn finger	577..597	CDD:275368	5/19 (26%)
		C2H2 Zn finger	605..625	CDD:275368	7/19 (37%)
		C2H2 Zn finger	633..653	CDD:275368	6/19 (32%)