DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and Zbtb43

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001342539.1	Gene:	Zbtb43 / 71834	MGIID:	1919084	Length:	504	Species:	Mus musculus

Alignment Length:	344	Identity:	66/344 - (19%)
Similarity:	123/344 - (35%)	Gaps:	66/344 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    97 YEIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQE 161
            :|:|...:.|....:.:.:.::|:|..:...| .:..:|:.|.|.|..:...|..:...:|.|
Mouse   192 FELGSGGHTDFPKAQELRDGENEEESTKDELS-SQVTEHEYLPSNSSTEHDRLSTEMASQDGE-- 253

  Fly   162 ECGMELDLDSEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAP 226
                      ||.:.:         |:.:.:|.:..:..:..|:..:.
Mouse   254 ----------EGTNDS---------TEFHYTRPLYSKPSIMAHRRWIH----------------- 282

  Fly   227 VKSAAQEYKCEHCGKIYHGKYSLRQ------HLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDE 285
            ||....|...:  |...|..|...|      .::.||.....|....|..:|.:.::.    .||
Mouse   283 VKPERLEQAWD--GMDVHAAYDEHQVTESVNTMQTDHSAQPSGAEEEFQIVEKKVEVE----FDE 341

  Fly   286 --------HMVQAHGGAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNH 342
                    ..|..:|.:.....|.:      |..:.:.|..|..:...:....:....|:...:|
Mouse   342 QAEGSSYDEQVDFYGSSMEEFSGEK------LGGNLIGHKQEAALAAGYSENIEMAMGIKEEASH 400

  Fly   343 GKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMHSTERP 407
            .......|.:.|: ||.|..:|.....|:..|.|.||:||.||.|:|.....|..||.:|:..:|
Mouse   401 LGFSATDKLYPCQ-CGKSFTHKSQRDRHMSMHLGLRPYGCSVCGKKFKMKHHLVGHMKIHTGIKP 464

  Fly   408 HVCSVCGATFSRQKGLYHH 426
            :.|::|...|..:...:.|
Mouse   465 YECNICAKRFMWRDSFHRH 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	2/19 (11%)
		zf-C2H2_8	323..411	CDD:292531	24/87 (28%)
		C2H2 Zn finger	327..346	CDD:275368	2/18 (11%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	367..389	CDD:290200	10/21 (48%)
		C2H2 Zn finger	382..402	CDD:275368	8/19 (42%)
		zf-H2C2_2	395..419	CDD:290200	8/23 (35%)
		C2H2 Zn finger	410..430	CDD:275368	4/17 (24%)
		C2H2 Zn finger	438..458	CDD:275368
Zbtb43	NP_001342539.1	BTB	60..160	CDD:306997
		C2H2 Zn finger	413..431	CDD:275368	5/18 (28%)
		C2H2 Zn finger	439..459	CDD:275368	8/19 (42%)
		zf-H2C2_2	451..474	CDD:316026	7/22 (32%)
		C2H2 Zn finger	467..484	CDD:275368	4/17 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000