DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and ZIPIC

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_651765.1	Gene:	ZIPIC / 43566	FlyBaseID:	FBgn0039740	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	104/398 - (26%)
Similarity:	161/398 - (40%)	Gaps:	57/398 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 HVQNIHFENGL-LKTEATDAGANL---KQERDREREPNSPVPIVAQVNPFAWYEIGGDHNEDSDD 109
            |.|..:.|:.| .:|..:....|:   :|:.:.|:|..|....|..|.|      .|...|.:::
  Fly    88 HKQTSYKEDDLDRETTISKFDGNIEEAQQQDEEEQELESVGTTVTLVGP------AGIVEEVAEE 146

  Fly   110 ERVVLEKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEECGMELDLDSEGR 174
            |...:.||.|:|||.....:....|::.:.:|             ||..|.||...|::   |..
  Fly   147 EHTFIIKQSEEEDEFHSVDLELDIDNEIIINE-------------EEAHEVEEVAHEIE---EVA 195

  Fly   175 HSAKIPHSCPHCTKVYQSRKVLERHIMR---QHKDTLSPDVDSEDADYEPPKDAPVKSAAQEY-- 234
            |..:.....||..:..|.....:...|.   :|.|.....:.|:..|.|...:     ::.||
  Fly   196 HEIEEEDLLPHDKQEAQEEDFFKEDTMSDFDEHLDGAIEYIISDGEDQEQDNE-----SSGEYTV 255

  Fly   235 --KCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAHGGA--- 294
              :|..|.:.:..:.:...|.||:|..|       :.|.:|...|........|: |.|...
  Fly   256 NIQCPSCPEKFSSRRAYNVHTKREHFPG-------YVCDQCGKTLQSYSGFIGHL-QNHEPVKQF 312

  Fly   295 ACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGKVH-TEQKNFVCESCG 358
            ||.||..|:..:..||.|...|:.|....|  ..|.|||.....:..|..:| :|.|...|:.||
  Fly   313 ACPVCPERFSRKFRLKHHMAWHSGETPYQC--DVCSKRFVHKVALYKHKMIHDSETKRLECQVCG 375

  Fly   359 YSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMHST-----ERPHVCSVCGATFS 418
            :..|.|..|..|:|||||::||.|.||:|||.....::.|:..|.:     .|...||.|..||.
  Fly   376 FKTRTKAHLERHMRSHTGDKPFACPVCNKRFSQMYNMKAHLREHESPGTNRHRRFHCSKCTHTFI 440

  Fly   419 RQKGLYHH 426
            .::....|
  Fly   441 NEQNYDAH 448

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	7/19 (37%)
		zf-C2H2_8	323..411	CDD:292531	32/93 (34%)
		C2H2 Zn finger	327..346	CDD:275368	5/18 (28%)
		C2H2 Zn finger	354..374	CDD:275368	8/19 (42%)
		zf-H2C2_2	367..389	CDD:290200	13/21 (62%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	8/28 (29%)
		C2H2 Zn finger	410..430	CDD:275368	6/17 (35%)
		C2H2 Zn finger	438..458	CDD:275368
ZIPIC	NP_651765.1	C2H2 Zn finger	286..306	CDD:275368	5/20 (25%)
		C2H2 Zn finger	314..334	CDD:275368	7/19 (37%)
		zf-H2C2_2	327..351	CDD:290200	10/25 (40%)
		C2H2 Zn finger	342..391	CDD:275368	17/50 (34%)
		zf-H2C2_2	383..408	CDD:290200	15/24 (63%)
		C2H2 Zn finger	399..419	CDD:275368	7/19 (37%)
		C2H2 Zn finger	432..449	CDD:275368	6/17 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	59	1.000	Inparanoid score	I2552
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.960