DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and CG31388

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_650060.1	Gene:	CG31388 / 41355	FlyBaseID:	FBgn0051388	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	379	Identity:	83/379 - (21%)
Similarity:	140/379 - (36%)	Gaps:	85/379 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   115 EKQDEDEDERPG-------------RSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEECGME 166
            |.||::.||...             :|:...|....|:::|........:....|...:.|.
  Fly   124 EPQDKNTDELASIKTTTTTEYMNAYQSVASPQSSPELSTDSQLSNEHFDMGLSPESEPESEA--- 185

  Fly   167 LDLDSEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAA 231
              :|:....|:   |:|..|...:::...|:.|  :.|...:.||.
  Fly   186 --IDNRDTSSS---HTCSKCGLEFENVDELKLH--KYHLHDIPPDT------------------- 224

  Fly   232 QEYKCEHCGKIYHGKYSLRQH-----LKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAH 291
             ::.|:||.:.:....:|.:|     |...|           :|.:|::|.....||:.|..:..
  Fly   225 -KFVCDHCDEGFRSAAALTRHCNMINLPLTH-----------SCTKCKSQFHNHILLETHKQRCL 277

  Fly   292 GGAA----CVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGKVHTEQKNF 352
            ...|    |.:||:...|...||.|.::|...|...|..  |...|:|...:.:|.|.||.::.:
  Fly   278 RPPASQHVCHICGKHLTTAFNLKNHLVRHAGTRRHKCDQ--CSASFYTAAELCSHQKTHTTERPY 340

  Fly   353 VCE-SCGYSCRNKETLRVHIRSH--TGERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVCSVCG 414
            :|. :||.:.|......:|.|.|  ..:|.:.|:.|.|.:.:.|..|.|...|:..|.|.|.:|.
  Fly   341 ICRYNCGKTFRFCSARSMHERVHMDASKRIYQCEYCPKSYVTPSECRTHQKYHNLTRDHGCEICR 405

  Fly   415 ATFSRQKGLYHHKFLHADTKQFVCKLCGNAY----AQAAGLAGHMRKHRNDELN 464
            .:|...|....|             |..||:    |:|...|....:.||...|
  Fly   406 ISFKTAKHYRSH-------------LKSNAHKTLEARAKAAASPNSRGRNCSTN 446

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	7/19 (37%)
		zf-C2H2_8	323..411	CDD:292531	25/90 (28%)
		C2H2 Zn finger	327..346	CDD:275368	5/18 (28%)
		C2H2 Zn finger	354..374	CDD:275368	6/20 (30%)
		zf-H2C2_2	367..389	CDD:290200	7/23 (30%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-H2C2_2	395..419	CDD:290200	8/23 (35%)
		C2H2 Zn finger	410..430	CDD:275368	5/19 (26%)
		C2H2 Zn finger	438..458	CDD:275368	6/23 (26%)
CG31388	NP_650060.1	zf-AD	4..76	CDD:285071
		C2H2 Zn finger	228..254	CDD:275368	6/25 (24%)
		C2H2 Zn finger	286..306	CDD:275368	7/19 (37%)
		C2H2 Zn finger	314..334	CDD:275368	6/21 (29%)
		C2H2 Zn finger	342..363	CDD:275368	6/20 (30%)
		C2H2 Zn finger	373..393	CDD:275368	6/19 (32%)
		C2H2 Zn finger	401..419	CDD:275368	5/30 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100