DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and CG8319

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_649920.2	Gene:	CG8319 / 41165	FlyBaseID:	FBgn0037722	Length:	383	Species:	Drosophila melanogaster

Alignment Length:	365	Identity:	92/365 - (25%)
Similarity:	149/365 - (40%)	Gaps:	49/365 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   117 QDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKE-----------EDSEQEECGMELDLD 170
            |.:.:|..|.:..|... |.:.|:...:  |..:.:||:           :|...||..:.::..
  Fly    43 QLDPDDAMPQKMCISCV-HDARTAYGFK--RRCEENYKKFYLAILNGQVIKDEPNEEDFLFIENP 104

  Fly   171 SEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDAPVKSAAQEYK 235
            .:|...||               |.|.:.|.:.|:........|........:...:|:  |.:|
  Fly   105 DKGNLEAK---------------KKLNKEIKKTHQTASRTTKSSITTSRAGRQLRSIKN--QTFK 152

  Fly   236 CEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAHGGAA--CVV 298
            ||.|.|.:..:.:|..|:| .|.|..       .|..||.:......||.|....:..:.  |..
  Fly   153 CELCIKQFKRQINLLDHMK-VHSNSH-------VCQNCEERFLFKADLDNHQCYRNSNSTVECPE 209

  Fly   299 CGRRYKTRHELKRHQLKHTSERN-VPCPHPGCGKRFFTIRHMRNHGKVHTEQKN----FVCESCG 358
            |.:.:.:...|..|:.|...||: ..|||  |.:.|...::::.|..:|.|.|.    ..|..|.
  Fly   210 CLKVFSSTQSLDSHKCKDMQERSPFQCPH--CQQAFTREQNLKAHLLIHAESKQGNGPHKCSYCQ 272

  Fly   359 YSCRNKETLRVHIRSHTGERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVCSVCGATFSRQKGL 423
            ....||..|:|||.:|.||||..|..|...|.|...|:.|:.:|:.|:|:.|..|..|||....|
  Fly   273 TGFFNKSALKVHIHAHMGERPHACPFCVSNFRSKQALKVHIRIHTGEKPYQCPHCPKTFSDNNNL 337

  Fly   424 YHHKFLHADTKQFVCKLCGNAYAQAAGLAGH-MRKHRNDE 462
            ..|:..|:|.:.:.|.:|...:.:...|..| :.|||:.:
  Fly   338 AKHRRRHSDERPYKCSICLQDFREKHHLKRHFLGKHRDGD 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	4/19 (21%)
		zf-C2H2_8	323..411	CDD:292531	31/91 (34%)
		C2H2 Zn finger	327..346	CDD:275368	3/18 (17%)
		C2H2 Zn finger	354..374	CDD:275368	8/19 (42%)
		zf-H2C2_2	367..389	CDD:290200	11/21 (52%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-H2C2_2	395..419	CDD:290200	9/23 (39%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368	4/20 (20%)
CG8319	NP_649920.2	zf-AD	4..79	CDD:285071	9/38 (24%)
		COG5048	<153..368	CDD:227381	65/224 (29%)
		C2H2 Zn finger	153..173	CDD:275368	7/20 (35%)
		C2H2 Zn finger	179..196	CDD:275368	5/16 (31%)
		C2H2 Zn finger	207..227	CDD:275370	4/19 (21%)
		C2H2 Zn finger	236..256	CDD:275368	6/21 (29%)
		C2H2 Zn finger	268..288	CDD:275368	8/19 (42%)
		C2H2 Zn finger	296..316	CDD:275368	6/19 (32%)
		zf-H2C2_2	308..332	CDD:290200	8/23 (35%)
		zf-C2H2	322..344	CDD:278523	7/21 (33%)
		C2H2 Zn finger	324..344	CDD:275368	7/19 (37%)
		C2H2 Zn finger	352..368	CDD:275368	3/15 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100