DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2129 and CG2199

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_728599.1	Gene:	CG2199 / 38159	FlyBaseID:	FBgn0035213	Length:	733	Species:	Drosophila melanogaster

Alignment Length:	397	Identity:	77/397 - (19%)
Similarity:	142/397 - (35%)	Gaps:	83/397 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SFVFGDFLLHVQNIHFENGLLKTEATDAGANLKQERDREREPN-------SPVPIVAQVNPFAWY 97
            |||.|      .|.:.|..::...........|::..|..|.|       :|...|:.... |:.
  Fly   136 SFVNG------ANTNTEIEIISASPKKLDKTPKKQISRLFEDNLNDSVKLTPAKEVSSTKK-AFL 193

  Fly    98 EIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEE 162
            .:.|:...|:.:   ||.:.:|:||...|...|...:.|....|...:   ....|||.
  Fly   194 NLFGNGGNDAIE---VLTESEEEEDSDKGPITINTNNFQCPECEFHAK---FPKPYKEH------ 246

  Fly   163 CGMELDLDSEGRHSAKIP--HSCPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKDA 225
                  |..|  |..:.|  :.|..|.|.:...|.|:.|:...|..|...:..::..:   .|:.
  Fly   247 ------LQKE--HGLQRPRIYPCTLCIKTFGVLKTLKNHLRDTHSRTFESEAKTKAKE---SKEK 300

  Fly   226 PVKSAAQ---EYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHM 287
            ..||.|:   :.|.:....:     |.|:..|......::      |.::|..:...:..:|:.:
  Fly   301 EAKSGAKNKIDAKAKETNAV-----SQRKKPKEKKSKEKK------TEIKCNVETKVVDEIDDQV 354

  Fly   288 VQAHG--------GAACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGK 344
            ....|        ..|..:...:......:|:..|::..:          .:..|.|    |...
  Fly   355 NNKKGTDSEDADQTQATKIASFKALNESLMKKRMLENVID----------SEYTFAI----NGSS 405

  Fly   345 VHT---EQKNFVCESCGYSCRNKETLRVHIRS-HTGERP--FGCQVCDKRFPSHSGLREHMAMHS 403
            ..|   :..||.||.|.......:.::.|::: |:.::|  |.|.||:|...:...|:.||.:|:
  Fly   406 ASTPRADSNNFQCEICDCELMTAKQMQEHMKTVHSIDKPKVFKCHVCEKSLATKQSLKTHMTLHA 470

  Fly   404 --TERPH 408
              .|.|:
  Fly   471 DGAEAPN 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	2/19 (11%)
		zf-C2H2_8	323..411	CDD:292531	23/94 (24%)
		C2H2 Zn finger	327..346	CDD:275368	3/18 (17%)
		C2H2 Zn finger	354..374	CDD:275368	4/20 (20%)
		zf-H2C2_2	367..389	CDD:290200	8/24 (33%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	6/16 (38%)
		C2H2 Zn finger	410..430	CDD:275368
		C2H2 Zn finger	438..458	CDD:275368
CG2199	NP_728599.1	C2H2 Zn finger	418..439	CDD:275370	4/20 (20%)
CG2199	NP_728599.1	C2H2 Zn finger	449..469	CDD:275370	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457891
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930