DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and az2

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_610289.2	Gene:	az2 / 35682	FlyBaseID:	FBgn0025185	Length:	593	Species:	Drosophila melanogaster

Alignment Length:	425	Identity:	101/425 - (23%)
Similarity:	164/425 - (38%)	Gaps:	70/425 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 NIHFENGLLKTEATDAGANLKQ-ERDREREPNSPVPIVAQVNPFAWYEIGGDHNEDSD-DERVVL 114
            |:|.....||...|...|.... .|.::.:..:.||:        :|     |.:.|. .||..|
  Fly   197 NLHLTAYKLKKCITSLHAQYASISRQKKTQKLTKVPL--------YY-----HGKYSFLAERGSL 248

  Fly   115 EKQDEDEDERPGRSIIKWQDHQSLTSESLRQVRALKVDYKEEDSEQEECGMEL---------DLD 170
            |..|.|:.:..|:..:.:.:...||::.:.........|  :.:.:..|.:.:         ||.
  Fly   249 EDADSDDVDGDGKIKLVFTEENQLTTQFIDLYSKFPQLY--DPAHKHFCNLNVRKSSLIEITDLL 311

  Fly   171 SEGRHSAKIPHSCPHCTKVYQSRKVLERHIMRQHK---DTLSPDVDSEDADYEPPKDA--PVKSA 230
            :.......:.|     ..||.|.:.:.:...|:.|   |.....:...:..|....::  |.||.
  Fly   312 TSEFSLGLVTH-----YDVYDSIQSMRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNSFMPTKSF 371

  Fly   231 AQEYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAH--GG 293
            .|:.|||.|...:...::|:.|..|||..|:.|.   |.|..||....|...|.:|..:.|  ..
  Fly   372 RQKLKCEVCEHSFSTDHALQAHQFRDHKMGDGGW---FRCTLCELNFDRKCHLQQHSQRVHMDKS 433

  Fly   294 AACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIRHMRNHGKVHTEQKNFVCESCG 358
            ..|.:|.|.:...::|..|:                          |.|.:.|. .|.||||.||
  Fly   434 FVCEICSRSFAFGNQLAIHK--------------------------RTHDEKHV-AKPFVCEFCG 471

  Fly   359 YSCRNKETLRVHIRS-HTGERPFGCQVCDKRFPSHSGLREHMAMHSTERPHVCSVCGATFSRQKG 422
            ...:.|..:..|:.: ||..|.|.|.:|.|.|.:...|::|:..|...|..||.||...|:....
  Fly   472 KCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFLTKRDLKDHVKAHLNIRDKVCEVCQKAFTNANA 536

  Fly   423 LYHHKFLHADTKQFVCKLCGNAYAQAAGLAGHMRK 457
            |..|:.:|.: |...|.||...:::...|..|||:
  Fly   537 LVKHRHIHKE-KTLQCSLCTTRFSERVSLGVHMRR 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	5/19 (26%)
		zf-C2H2_8	323..411	CDD:292531	25/88 (28%)
		C2H2 Zn finger	327..346	CDD:275368	2/18 (11%)
		C2H2 Zn finger	354..374	CDD:275368	6/20 (30%)
		zf-H2C2_2	367..389	CDD:290200	8/22 (36%)
		C2H2 Zn finger	382..402	CDD:275368	6/19 (32%)
		zf-H2C2_2	395..419	CDD:290200	9/23 (39%)
		C2H2 Zn finger	410..430	CDD:275368	6/19 (32%)
		C2H2 Zn finger	438..458	CDD:275368	7/20 (35%)
az2	NP_610289.2	MADF_DNA_bdg	157..242	CDD:287510	12/57 (21%)
		GT1	276..>341	CDD:304916	9/71 (13%)
		C2H2 Zn finger	377..398	CDD:275368	6/20 (30%)
		C2H2 Zn finger	408..429	CDD:275368	6/20 (30%)
		C2H2 Zn finger	436..456	CDD:275368	6/45 (13%)
		C2H2 Zn finger	467..488	CDD:275368	6/20 (30%)
		C2H2 Zn finger	496..516	CDD:275368	6/19 (32%)
		C2H2 Zn finger	524..544	CDD:275368	6/19 (32%)
		C2H2 Zn finger	551..572	CDD:275368	7/20 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930