DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and zf30C

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_477301.1	Gene:	zf30C / 34292	FlyBaseID:	FBgn0270924	Length:	777	Species:	Drosophila melanogaster

Alignment Length:	593	Identity:	122/593 - (20%)
Similarity:	193/593 - (32%)	Gaps:	191/593 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DTYAGMANAKCGEIYFQSLHSFRIDCAFCEMKSFVFGDFLLHVQNIHFENGLLKTEATDAGANLK 72
            :.|......||||.......|..::|..|..:.....:...|.::.....|..:.::..:...:|
  Fly   109 EAYRRHCRTKCGEEKLPREESRPMECKCCYTRFSSASNLSKHRRSRPDTCGQPEYDSPGSSDGMK 173

  Fly    73 QERDREREPNSPVPIVAQVNPFAWYEIGGDHNEDSDDERVVLEKQDEDEDERPGRSIIKWQ-DHQ 136
            :.:...::                     |.|.|||||....|:.::.:|:.|..|.:|.: ..:
  Fly   174 KHKAFRKK---------------------DRNRDSDDEDTTSEESEDSDDDIPLASRLKTKLKQE 217

  Fly   137 SLTSES----------------------LRQVRALKVD-YKEEDSEQEECGMELDLDSEGRHSAK 178
            |..|:|                      |.....:||: :.|||.|.::..|.:..:|
  Fly   218 SQNSDSGDECPDFEPNNSEDDADASGFQLPPPAMVKVEAFDEEDFEYQDASMYVKTES------- 275

  Fly   179 IPHSCPHCTKVYQSRKVLERHIMRQHKDTLSP----------------------DVDSEDA---- 217
                    |.::.:.|.....::....|.|.|                      :|..||.
  Fly   276 --------TDIFSNEKDKLLDVLLNEGDGLKPFESLKVEQGAGILDEIAAVPLVEVAEEDVLELR 332

  Fly   218 ------------DYEPPKD-------------AP-----------------------------VK 228
                        ...|||:             ||                             :.
  Fly   333 GHQMEKPPGPRKRGRPPKEKIPVVKRKYRKRNAPRSPSPDDSSGTPKRVAKISKKELKERLKMIN 397

  Fly   229 SAAQEYKCEHCGKIYHGKYSLRQHLKRDHDNGEEGGSAIFTCLECEAQLPRLRLLDEHMVQAHGG 293
            ...:.:||.||.||||.:....:||:.||...|.....||..::..|:      |||.:.:
  Fly   398 KMEKSWKCPHCVKIYHIRKPYEKHLRDDHKLNEAEMKEIFKDVDVHAK------LDEEVFK---- 452

  Fly   294 AACVVCGRRYKTRHELKRHQLKHTSERNVPCPHPGCGKRFFTIR--------------------- 337
              |.:|.:.|.....|..|...|..:..:....|.....||..:
  Fly   453 --CPICSKIYLVEKRLVTHMKVHGEDGKLTFKCPCYCNLFFATKEQATEHARAQHKELLYCEKCD 515

  Fly   338 -----------HMRN-HGK--VHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERP-FGCQVCDK 387
                       |.|| |.|  ..::|:|.:|:.||.....:.:|..|:||..|..| :||.||.|
  Fly   516 KYMTGHDSLKNHERNFHSKKEPRSQQRNLICDKCGKKFTGRTSLSDHVRSDCGRLPLYGCSVCGK 580

  Fly   388 RFPSHSGLREHMAMHSTERPHVCSVCGATFSRQKGLY--HHKFLHADTKQFVCKLCGNAYAQAAG 450
            ...:...|:.||.:|..:.|:.|..||.|| :.|..|  |.|..|.|.|.:.|.||...|.....
  Fly   581 HLSTAGILKTHMLLHKADTPYQCDKCGKTF-KVKAQYKSHLKTRHTDYKPYKCHLCPKEYPYRES 644

  Fly   451 LAGHMRKH 458
            |..||..|
  Fly   645 LLTHMTVH 652

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	5/19 (26%)
		zf-C2H2_8	323..411	CDD:292531	29/123 (24%)
		C2H2 Zn finger	327..346	CDD:275368	8/53 (15%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	367..389	CDD:290200	11/22 (50%)
		C2H2 Zn finger	382..402	CDD:275368	7/19 (37%)
		zf-H2C2_2	395..419	CDD:290200	10/23 (43%)
		C2H2 Zn finger	410..430	CDD:275368	9/21 (43%)
		C2H2 Zn finger	438..458	CDD:275368	7/19 (37%)
zf30C	NP_477301.1	C2H2 Zn finger	33..53	CDD:275368
		C2H2 Zn finger	61..82	CDD:275368
		C2H2 Zn finger	98..117	CDD:275368	1/7 (14%)
		C2H2 Zn finger	134..152	CDD:275368	3/17 (18%)
		C2H2 Zn finger	511..532	CDD:275370	3/20 (15%)
		COG5048	<523..>672	CDD:227381	46/131 (35%)
		C2H2 Zn finger	546..566	CDD:275368	6/19 (32%)
		C2H2 Zn finger	575..595	CDD:275368	7/19 (37%)
		C2H2 Zn finger	603..624	CDD:275368	9/21 (43%)
		C2H2 Zn finger	632..652	CDD:275368	7/19 (37%)
		C2H2 Zn finger	660..680	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45440037
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840