DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2129 and Zscan10

DIOPT Version :9

Sequence 1:	NP_572449.1	Gene:	CG2129 / 31741	FlyBaseID:	FBgn0030008	Length:	465	Species:	Drosophila melanogaster
Sequence 2:	NP_001028597.2	Gene:	Zscan10 / 332221	MGIID:	3040700	Length:	782	Species:	Mus musculus

Alignment Length:	338	Identity:	98/338 - (28%)
Similarity:	150/338 - (44%)	Gaps:	53/338 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   164 GMELDLDSEGRHSAKIPHS----CPHCTKVYQSRKVLERHIMRQHKDTLSPDVDSEDADYEPPKD 224
            |..|..:.||:  .|:|..    |.||.:.::.|..|:|| :|.|         ::|.|:...:|
Mouse   459 GKNLTPNPEGK--TKVPEMAAVLCSHCGQTFKRRSSLKRH-LRNH---------AKDKDHLSSED 511

  Fly   225 APVKSAAQE---YKCEHCGKIYHGKYSLRQHLKRDH----------------DNGE-------EG 263
            ....|::||   |.|..|||.:.....|..|.:|.|                .|.:       ..
Mouse   512 PGSLSSSQESNPYVCSDCGKAFRQSEQLMIHTRRVHTRERPFSCQVCGRCFTQNSQLISHQQIHT 576

  Fly   264 GSAIFTCLECEAQLPRLRLLDEHMVQAHGGAA---CVVCGRRYKTRHELKRHQLKHTSERNVPCP 325
            |.....|.:|..:..|...|..|:: .||...   |..||:.::...:|.||...||.|:  ||.
Mouse   577 GEKPHACPQCSKRFVRRAGLARHLL-THGSLRPYHCAQCGKSFRQMRDLTRHVRCHTGEK--PCR 638

  Fly   326 HPGCGKRFFTIRHMRNHGKVHTEQKNFVCESCGYSCRNKETLRVHIRSHTGERPFGCQVCDKRFP 390
            ...||:.|....|:..|.::||.:|...|:.||:..||...|..|.||||||||:.|..|.:.|.
Mouse   639 CNECGEGFTQNAHLARHQRIHTGEKPHACDICGHRFRNSSNLARHRRSHTGERPYSCPTCGRSFR 703

  Fly   391 SHSGLREHMAMHS-----TERPHVCSVCGATFSRQKGLYHHKFLHADTKQFVCKLCGNAYAQAAG 450
            .::.|:.|:..|:     .|.|..|..||.:|:|...|..|..:|...:.:.|.|||.::::.:.
Mouse   704 RNAHLQRHLITHTGSKQEKEVPQECPECGKSFNRSCNLLRHLLVHTGARPYSCALCGRSFSRNSH 768

  Fly   451 LAGHMRKHRNDEL 463
            |..|:|.|..:.|
Mouse   769 LLRHLRTHARESL 781

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2129	NP_572449.1	C2H2 Zn finger	296..316	CDD:275370	6/19 (32%)
		zf-C2H2_8	323..411	CDD:292531	33/92 (36%)
		C2H2 Zn finger	327..346	CDD:275368	5/18 (28%)
		C2H2 Zn finger	354..374	CDD:275368	8/19 (42%)
		zf-H2C2_2	367..389	CDD:290200	12/21 (57%)
		C2H2 Zn finger	382..402	CDD:275368	5/19 (26%)
		zf-H2C2_2	395..419	CDD:290200	9/28 (32%)
		C2H2 Zn finger	410..430	CDD:275368	7/19 (37%)
		C2H2 Zn finger	438..458	CDD:275368	7/19 (37%)
Zscan10	NP_001028597.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..37
		SCAN	39..123	CDD:153421
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	197..233
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	290..321
		C2H2 Zn finger	345..372	CDD:275368
		COG5048	366..767	CDD:227381	93/322 (29%)
		C2H2 Zn finger	380..400	CDD:275368
		zf-H2C2_2	393..417	CDD:290200
		C2H2 Zn finger	408..428	CDD:275368
		C2H2 Zn finger	436..456	CDD:275368
		C2H2 Zn finger	480..500	CDD:275368	8/20 (40%)
		zf-C2H2	480..500	CDD:278523	8/20 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	491..522		11/40 (28%)
		C2H2 Zn finger	526..547	CDD:275368	7/20 (35%)
		zf-C2H2	553..575	CDD:278523	1/21 (5%)
		C2H2 Zn finger	555..575	CDD:275368	1/19 (5%)
		zf-H2C2_2	568..592	CDD:290200	3/23 (13%)
		C2H2 Zn finger	583..603	CDD:275368	5/20 (25%)
		SIR2	<592..>643	CDD:294129	16/53 (30%)
		C2H2 Zn finger	611..631	CDD:275368	6/19 (32%)
		zf-H2C2_2	623..648	CDD:290200	11/26 (42%)
		C2H2 Zn finger	639..659	CDD:275368	5/19 (26%)
		zf-H2C2_2	651..676	CDD:290200	8/24 (33%)
		C2H2 Zn finger	667..687	CDD:275368	8/19 (42%)
		zf-H2C2_2	679..704	CDD:290200	13/24 (54%)
		C2H2 Zn finger	695..715	CDD:275368	5/19 (26%)
		C2H2 Zn finger	728..748	CDD:275368	7/19 (37%)
		zf-C2H2	754..776	CDD:278523	7/21 (33%)
		C2H2 Zn finger	756..776	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000