DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment alpha-PheRS and Fdxacb1

DIOPT Version :9

Sequence 1:	NP_572448.1	Gene:	alpha-PheRS / 31740	FlyBaseID:	FBgn0030007	Length:	498	Species:	Drosophila melanogaster
Sequence 2:	NP_941077.2	Gene:	Fdxacb1 / 382137	MGIID:	3584513	Length:	622	Species:	Mus musculus

Alignment Length:	234	Identity:	44/234 - (18%)
Similarity:	74/234 - (31%)	Gaps:	78/234 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   102 VGFSKAMSHGWILVDKSVTPPLVRRKVDTITDVVRNQLQQVALGKGDQLPAKEVADFKKRKLLQE 166
            :||...|.       :|..|.|:....|.:.:::...||:     |..|....       :.:.:
Mouse   396 LGFDNNMK-------ESCLPSLLGHLKDALGNLLTQTLQE-----GSSLGTSV-------EFVLQ 441

  Fly   167 TTTKSFV-----LARGPEFATTLTKLETDLTVEMLANGLWDQLKFKAYNFDALGAPPTRGHLHPL 226
            ...|.::     |..||:.|..|. :.:.||.:::.: ......|.:.|.|.|
Mouse   442 PNGKDYIIHVKSLNFGPDCAENLI-IGSILTSKIVKH-KHQCFVFVSINLDLL------------ 492

  Fly   227 LKVRTEFRQIFLEMGFSEMPTNNYVESSFWNFDALYQPQQHPARDAHDTFFVNHPAKSHK-FPQD 290
                     :.|..|.|:.       ...|.||..:..:..|.:..|        .||:. :|..
Mouse   493 ---------VMLAYGISDW-------RILWTFDNRFLKRFAPGKIEH--------FKSYSLYPPC 533

  Fly   291 YLERVKKVHSVGGYGSKGYGYDWKLEEAQKNLLRTHTTA 329
            |      ||.|.         .|..|:...:.|..||.|
Mouse   534 Y------VHDVS---------FWVDEKKAFDELEFHTVA 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
alpha-PheRS	NP_572448.1	PLN02853	4..496	CDD:215458	44/234 (19%)
alpha-PheRS	NP_572448.1	PheRS_alpha_core	224..483	CDD:238277	21/107 (20%)
Fdxacb1	NP_941077.2	DUF2431	7..176	CDD:287341
Fdxacb1	NP_941077.2	FDX-ACB	528..622	CDD:214893	11/45 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0016
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810