Protein Alignment Smox and Smad9

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_620227.2
• Gene: Smad9 / 85435
• RGDID: 71004
• Length: 430
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 253/493 - (51%)
• Similarity: 306/493 - (62%)
• Gaps: 79/493 - (16%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTRCVT 64
            :..||...|||||..|:|:|    |.||:||||.:||||: ||...::|||||:|.....::|||
  Rat    10 LFSFTSPAVKRLLGWKQGDE----EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSKCVT 70

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:|||||:.||:.|..:::|:|||||||:::|
  Rat    71 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYRRVE 135

  Fly   130 LSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYN-----AAIIRSASLSPPQYMELGGAGPVSV 189
            ..:|.|.                   .:|.:::||     .|..|||||.....|......|.|.
  Rat   136 TPVLPPV-------------------LVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYPDSF 181

  Fly   190 SSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPP 254
            ..|....|                .||....:.|.....|:.|:
  Rat   182 QQSLGPAP----------------PSSPGHVFPQSPCPTSYPQS--------------------- 209

  Fly   255 PGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVD 319
            ||..||...|..            .:|..||.|.||..|||::|||||.||||||.||..|:.:|
  Rat   210 PGSPSESDSPYQ------------HSDFRPVCYEEPLHWCSVAYYELNNRVGETFQASSRSVLID 262

  Fly   320 GFTDPSNS-ERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQ 383
            |||||||: .|||||||||||||..:|.|||||||||.|||:||||:|||:|||||||||.|||.
  Rat   263 GFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNY 327

  Fly   384 RYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQ 448
            ::|:|||||||||.||:||:||||.||.||:|||..|||.||:||:||||||||||||||||.||
  Rat   328 QHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQ 392

  Fly   449 TVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            .|||||||||:||:|||||||:||||||||..|.||:|
  Rat   393 DVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 430

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	68/123 (55%)
		MH2_SMAD_2_3	285..475	CDD:199826	145/190 (76%)
Smad9	NP_620227.2	MH1_SMAD_1_5_9	13..136	CDD:199814	70/126 (56%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..222		15/99 (15%)
		MH2	230..430	CDD:412135	152/199 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274383at33208
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920