Protein Alignment Smox and smad3a

DIOPT Version :10

• Sequence 1: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_571646.1
• Gene: smad3a / 58092
• ZFINID: ZDB-GENE-000509-3
• Length: 425
• Species: Danio rerio
• Alignment Length: 499
• Identity: 303/499 - (60%)
• Similarity: 348/499 - (69%)
• Gaps: 89/499 - (17%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKIKKNSQLEELERAISTQNCQTRCVTV 65
            :|||||.:|||||..||| |.|..|.||.|||||:||||:||..||:|||:||:||:..|:|:|:
Zfish     3 ILPFTPPIVKRLLGWKKG-EQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITTQDVNTKCITI 66

  Fly    66 PRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIEL 130
            |||.........||||||||||||||||||||.:||:.::.||:|||::|:|:|:|||||:::|.
Zfish    67 PRSLDGRLQVSHRKGLPHVIYCRLWRWPDLQSHHELRAIELCEFAFHMKKDEVCVNPYHYQRVET 131

  Fly   131 SILVPKSLPTPPDSIVDY-PLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSVSSSAS 194
            .:|.|..:|...:...:: |||:::|.||.||.:.|.|       .||
Zfish   132 PVLPPVLVPRHTEIPSEFPPLDDYSHSIPENTIFPAGI-------EPQ----------------- 172

  Fly   195 STPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPPPGYMS 259
                                    |.|                         ||.  ||||||:|
Zfish   173 ------------------------SNY-------------------------IPE--TPPPGYIS 186

  Fly   260 EDGDPIDPNDNMNMSRLTP--------PA----DAAPVMYHEPAFWCSISYYELNTRVGETFHAS 312
            |||:..|...|.:|...:|        ||    |..||.|.||||||||||||||.|||||||||
Zfish   187 EDGETSDHQMNRSMDTGSPNLSPNPVSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 251

  Fly   313 QPSITVDGFTDPSNSERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQ 377
            |||:|||||||||||||||||||||||||..||.||||||:|||||||||||||||||||:||||
Zfish   252 QPSLTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQ 316

  Fly   378 SPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWG 442
            ||||||||||||||||||||||||||||||||||||:|||:||||||||||||||||||||||||
Zfish   317 SPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWG 381

  Fly   443 AEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            |||||||||||||||||||||||||||:||||||||.:.|||:|
Zfish   382 AEYRRQTVTSTPCWIELHLNGPLQWLDKVLTQMGSPSIRCSSVS 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	74/122 (61%)
		MH2_SMAD_2_3	285..475	CDD:199826	177/189 (94%)
smad3a	NP_571646.1	MH1_SMAD_2_3	7..131	CDD:199815	76/124 (61%)
		MH2_SMAD_2_3	224..414	CDD:199826	177/189 (94%)