Protein Alignment Smox and smad6b

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001038516.1
• Gene: smad6b / 564395
• ZFINID: ZDB-GENE-050419-198
• Length: 486
• Species: Danio rerio
• Alignment Length: 444
• Identity: 118/444 - (26%)
• Similarity: 185/444 - (41%)
• Gaps: 113/444 - (25%)

  Fly    19 NEDNSVEGKWSEKAVKNLVKKIKKNSQLEELERAISTQNCQTRCVTVPRSKPAPAGEHLRKGLPH 83
            ::..||..:..:.|..:|:|::|:.: |:.|..|:.:....:.||.|.|:: ...|.|:..  |.
Zfish   153 SKPRSVMEQELKTATYSLLKRLKEKT-LDTLLEAVESGGMPSDCVMVSRTE-LRLGGHMAP--PQ 213

  Fly    84 VIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIELSILVPKSLPTPPDSIVDY 148
            ::.|:|:||.|||...:||.|..|:.........:|.|||||.:    :..|:| |.||.|
Zfish   214 LLICKLYRWSDLQHTAQLKALCECKSFGAQDGPVVCCNPYHYSR----LCGPES-PPPPYS---- 269

  Fly   149 PLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSVSSSASSTPATAAGGGGGPSSSSSS 213
                                   .|||.:..:     |:.:|.|..|...|.|  ...|:::...
Zfish   270 -----------------------RLSPSEEHK-----PLDLSDSTLSYTETEA--ASSPNATQGE 304

  Fly   214 SSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPPPGYMSEDGDPIDPNDNMNMSRLTP 278
            .|.|:                                                         |:|
Zfish   305 FSDAS---------------------------------------------------------LSP 312

  Fly   279 PADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLGLLSNVNRNEV 343
            .   ||...|    ||:::|:|..||||..:...||::::  |.|......||||.||...|:..
Zfish   313 D---APKQSH----WCNVAYWEHRTRVGRLYTVYQPAVSI--FYDLPQGTGFCLGQLSLDQRSST 368

  Fly   344 VEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 408
            |::||..||.|:.|......|:|...|...|||.||..:.. |.....|.|:.||.::|:|:.:.
Zfish   369 VQRTRGKIGYGLLLSKEPDGVWAYNRSQHPIFVNSPTLDVP-GSRSLVVRKVMPGYSIKVFDYER 432

  Fly   409 FAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 462
            .:.|...:.|:..:..|...   ::|:||.||||..|.||.:||.|||:|:.||
Zfish   433 SSMLRQGAESELLDGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLN 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	33/110 (30%)
		MH2_SMAD_2_3	285..475	CDD:199826	63/178 (35%)
smad6b	NP_001038516.1	MH1_SMAD_6	152..262	CDD:199817	33/116 (28%)
		MH2_SMAD_6	311..484	CDD:199824	66/186 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810