Protein Alignment Smox and Smad9

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_036019060.1
• Gene: Smad9 / 55994
• MGIID: 1859993
• Length: 456
• Species: Mus musculus
• Alignment Length: 496
• Identity: 253/496 - (51%)
• Similarity: 306/496 - (61%)
• Gaps: 82/496 - (16%)

  Fly     1 MLPFT---PQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTR 61
            ::|.|   ...|||||..|:|:|    |.||:||||.:||||: ||...::|||||:|.....::
Mouse    33 LVPMTSVDSPAVKRLLGWKQGDE----EEKWAEKAVDSLVKKLKKKKGAMDELERALSCPGQPSK 93

  Fly    62 CVTVPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYK 126
            |||:|||.........|||||||||||:||||||||.:|||||:.||:.|..:::|:|||||||:
Mouse    94 CVTIPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYR 158

  Fly   127 KIELSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYN-----AAIIRSASLSPPQYMELGGAGP 186
            ::|..:|.|.                   .:|.:::||     .|..|||||.....|......|
Mouse   159 RVETPVLPPV-------------------LVPRHSEYNPQLSLLAKFRSASLHSEPLMPHNATYP 204

  Fly   187 VSVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTG 251
            .|...|....|                .||....:.|                     |..|.:.
Mouse   205 DSFQQSLCPAP----------------PSSPGHVFPQ---------------------SPCPTSY 232

  Fly   252 TPPPGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSI 316
            ...||..||...|..            .:|..||.|.||..|||::|||||.||||||.||..|:
Mouse   233 PHSPGSPSESDSPYQ------------HSDFRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSV 285

  Fly   317 TVDGFTDPSNS-ERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPN 380
            .:||||||||: .|||||||||||||..:|.|||||||||.|||:||||:|||:|||||||||.|
Mouse   286 LIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRN 350

  Fly   381 CNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEY 445
            ||.::|:|||||||||.||:||:||||.||.||:|||..|||.||:||:||||||||||||||||
Mouse   351 CNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEY 415

  Fly   446 RRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            .||.|||||||||:||:|||||||:||||||||..|.||:|
Mouse   416 HRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	68/123 (55%)
		MH2_SMAD_2_3	285..475	CDD:199826	145/190 (76%)
Smad9	XP_036019060.1	MH1_SMAD_1_5_9	41..162	CDD:199814	68/124 (55%)
		MH2	256..456	CDD:412135	152/199 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810