Protein Alignment Smox and smad9

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001007479.1
• Gene: smad9 / 493210
• XenbaseID: XB-GENE-484686
• Length: 466
• Species: Xenopus tropicalis
• Alignment Length: 507
• Identity: 263/507 - (51%)
• Similarity: 323/507 - (63%)
• Gaps: 71/507 - (14%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTRCVT 64
            :..||...|||||..|:|:|    |.||:||||.:||||: ||...:||||||:|.....::|||
 Frog    10 LFSFTSPAVKRLLGWKQGDE----EEKWAEKAVDSLVKKLKKKKGAMEELERALSCPGQPSKCVT 70

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:||||::.||:.|..:::::|||||||:::|
 Frog    71 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPMECCEFPFGSKQKDVCINPYHYRRVE 135

  Fly   130 LSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYN-----AAIIRSASLSPPQYMELGGAGPVSV 189
            ..:|.|.                   .:|.::::|     .|..|:.||:....|......|.|.
 Frog   136 TPVLPPV-------------------LVPRHSEFNPQLSLLAKFRNTSLNNEPLMPHNATFPESF 181

  Fly   190 SSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPP 254
            ......||               .|||.::.:.|....:.:   .||..|....||....|.|||
 Frog   182 QQQPPCTP---------------FSSSPSNIFPQSPTTVGY---PDSPQSSADPGSPYQITETPP 228

  Fly   255 PGYMSEDGDPIDPNDNMNMSRLTPPADAA--------------PVMYHEPAFWCSISYYELNTRV 305
            |.|.:.|   |..|.|      .|.||.|              ||.|.||..|||::|||||.||
 Frog   229 PPYNAPD---IQGNQN------RPTADPAACQLVLSALNRDFRPVCYEEPLHWCSVAYYELNNRV 284

  Fly   306 GETFHASQPSITVDGFTDPSNSE-RFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECL 369
            ||||.||..|:.:||||||||:: |||||||||||||..:|.|||||||||.|||:||||:|||:
 Frog   285 GETFQASSRSVLIDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECV 349

  Fly   370 SDSSIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIR 434
            |||||||||.|||.::|:||:||||||.||:|||||||.||.||||||:||||.||:||:|||||
 Frog   350 SDSSIFVQSRNCNYQHGFHPSTVCKIPSGCSLKIFNNQLFAQLLSQSVNQGFEVVYELTKMCTIR 414

  Fly   435 MSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            |||||||||||.||.|||||||||:||:|||||||:||||||||..|.||:|
 Frog   415 MSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	67/123 (54%)
		MH2_SMAD_2_3	285..475	CDD:199826	147/190 (77%)
smad9	NP_001007479.1	MH1_SMAD_1_5_9	13..136	CDD:199814	69/126 (55%)
		PRK10263	<137..>249	CDD:236669	35/157 (22%)
		MH2_SMAD_1_5_9	266..466	CDD:199822	154/199 (77%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274383at33208
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920