Protein Alignment Smox and smad9

DIOPT Version :10

• Sequence 1: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001315428.1
• Gene: smad9 / 445564
• ZFINID: ZDB-GENE-031014-1
• Length: 466
• Species: Danio rerio
• Alignment Length: 504
• Identity: 274/504 - (54%)
• Similarity: 331/504 - (65%)
• Gaps: 65/504 - (12%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTRCVT 64
            :..||...|||||..|:|:|    |.||:||||.:||||: ||...:||||:|:|.....::|||
Zfish    10 LFSFTSPAVKRLLGWKQGDE----EEKWAEKAVDSLVKKLKKKKGAMEELEKALSCPGQPSKCVT 70

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:|||.||.||:.|..:::|||||||||:::|
Zfish    71 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKALDCCEFPFGSKQKEICINPYHYRRVE 135

  Fly   130 LSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYN-----AAIIRSASL--SP--PQYMELGGAG 185
            ..:|.|.                   .:|.::::|     .|..|:|||  .|  ||......:.
Zfish   136 TPVLPPV-------------------LVPRHSEFNPQHSLLAKFRNASLHNEPLMPQNATFPDSF 181

  Fly   186 PVSVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNT 250
            |....||.||:|           |||.:.|.||.::.            :|.||....||....|
Zfish   182 PAMPCSSFSSSP-----------SSSLNPSPAAHSFP------------NSPSSATEPGSPYQIT 223

  Fly   251 G-TPPPGYM------SEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGET 308
            . ||||.|.      |||..|.:.::| .:....|..|..||.|.||.:|||::|||||.|||||
Zfish   224 AETPPPPYSMMESSPSEDVKPAESSEN-KLILTAPQRDLRPVCYEEPEYWCSVAYYELNNRVGET 287

  Fly   309 FHASQPSITVDGFTDPSNSE-RFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDS 372
            ||||..||.|||||||||:: |||||||||||||..:|.|||||||||.|||:||||:|||||||
Zfish   288 FHASARSILVDGFTDPSNNKNRFCLGLLSNVNRNSTIEHTRRHIGKGVHLYYVGGEVYAECLSDS 352

  Fly   373 SIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSF 437
            ||||||.|||.::|:||.||||||.||:|||||||.||.||||||:.|||.||:||:||||||||
Zfish   353 SIFVQSRNCNYQHGFHPTTVCKIPSGCSLKIFNNQLFAQLLSQSVNHGFEVVYELTKMCTIRMSF 417

  Fly   438 VKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            ||||||||.||.|||||||||:||:|||||||:||||||||..|.||:|
Zfish   418 VKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNPISSVS 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	69/123 (56%)
		MH2_SMAD_2_3	285..475	CDD:199826	150/190 (79%)
smad9	NP_001315428.1	MH1_SMAD_1_5_9	13..136	CDD:199814	71/126 (56%)
		MH2_SMAD_1_5_9	266..466	CDD:199822	157/199 (79%)