Protein Alignment Smox and Mad

DIOPT Version :10

• Sequence 1: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001259992.1
• Gene: Mad / 33529
• FlyBaseID: FBgn0011648
• Length: 525
• Species: Drosophila melanogaster
• Alignment Length: 496
• Identity: 266/496 - (53%)
• Similarity: 326/496 - (65%)
• Gaps: 70/496 - (14%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKIKK-NSQLEELERAISTQNCQTRCVT 64
            :..||...||:||..|:|:|    |.||:||||.:||||:|| ...:||||||:|.....::|||
  Fly    90 LFSFTSPAVKKLLGWKQGDE----EEKWAEKAVDSLVKKLKKRKGAIEELERALSCPGQPSKCVT 150

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:|||||:.|:|.|..:::|:||||||||::|
  Fly   151 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLELCQYPFSAKQKEVCINPYHYKRVE 215

  Fly   130 LSILVPKSLP-----TPPDSIVDYPLDNHTHQ--IPNNTDYNAAIIRSASLSPPQYMELGGAGPV 187
            ..:|.|..:|     .|..|::.:   ||..:  :|:|..|:.:...|.||
  Fly   216 SPVLPPVLVPRHSEFAPGHSMLQF---NHVAEPSMPHNVSYSNSGFNSHSL-------------- 263

  Fly   188 SVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGT 252
                |.|:|..      |.|||.:|:.:|.                .||.:            ||
  Fly   264 ----STSNTSV------GSPSSVNSNPNSP----------------YDSLA------------GT 290

  Fly   253 PPPGYM-SEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSI 316
            |||.|. ||||:..:|||...:.. ....|.|.|.|.|||||.||:|||||.||||.||.:..|:
  Fly   291 PPPAYSPSEDGNSNNPNDGGQLLD-AQMGDVAQVSYSEPAFWASIAYYELNCRVGEVFHCNNNSV 354

  Fly   317 TVDGFTDPS-NSERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPN 380
            .|||||:|| ||:|.|||.|||||||..:|.|||||||||.|||:.|||:|||||||:|||||.|
  Fly   355 IVDGFTNPSNNSDRCCLGQLSNVNRNSTIENTRRHIGKGVHLYYVTGEVYAECLSDSAIFVQSRN 419

  Fly   381 CNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEY 445
            ||..:|:||:|||||||||:||||||||||.||||||:.||||||:||:||||||||||||||||
  Fly   420 CNYHHGFHPSTVCKIPPGCSLKIFNNQEFAQLLSQSVNNGFEAVYELTKMCTIRMSFVKGWGAEY 484

  Fly   446 RRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            .||.|||||||||:||:|||||||:||||||||....||:|
  Fly   485 HRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPHNAISSVS 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	69/123 (56%)
		MH2_SMAD_2_3	285..475	CDD:199826	147/190 (77%)
Mad	NP_001259992.1	MH1_SMAD_1_5_9	93..216	CDD:199814	71/126 (56%)
		MH2_SMAD_1_5_9	325..525	CDD:199822	153/199 (77%)