Protein Alignment Smox and smad7

DIOPT Version :10

• Sequence 1: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_778257.2
• Gene: smad7 / 326282
• ZFINID: ZDB-GENE-030128-3
• Length: 372
• Species: Danio rerio
• Alignment Length: 443
• Identity: 118/443 - (26%)
• Similarity: 178/443 - (40%)
• Gaps: 144/443 - (32%)

  Fly    35 NLVKKIKKNSQLEELERAISTQ-NCQTRCVTVPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQ 98
            :::||||: .|||.|.:|:.:: ..::.|:.:|....|..|:| ...||.::| :::|||||:..
Zfish    57 SILKKIKE-KQLEVLLQAVESRGGARSPCLLLPGKADARLGQH-SYPLPLLLY-KVFRWPDLRHS 118

  Fly    99 NELKPLDHCEYAFHLRKEEICINPYHYKKIELSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDY 163
            :|||.|..||....:..|.:|.||:|..::       ..|.:||.....||           ||:
Zfish   119 SELKRLSCCESYGKINPELVCCNPHHMSRL-------CELESPPPPYSRYP-----------TDF 165

  Fly   164 NAAIIRSASLSPPQYMELGGAGPVSVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQL 228
                     |.||              .|..|.||:...||...|:....|.|.|
Zfish   166 ---------LKPP--------------DSPGSVPASTETGGTAYSAPMGFSDSLA---------- 197

  Fly   229 SFGQNMDSQSSVLSVGSSIPNTGTPPPGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFW 293
                                         :.|.|                          |...|
Zfish   198 -----------------------------LQERG--------------------------EQPHW 207

  Fly   294 CSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLGLLSNVNRNEVVEQTRRHIGKGVRLY 358
            |.::|:|..||||..:...:||:  |.|.|......||||.|::.|::::|:..|..||.|::|.
Zfish   208 CVVAYWEEKTRVGRLYSVQEPSL--DIFYDLPQGTGFCLGQLASENKSQLVQMVRAKIGYGIQLS 270

  Fly   359 YIGGEVFAECLSDSSIFVQS---PNCNQRYGWHPATVCKIPPGCNLKIF-----------NNQEF 409
            .....|:....|...||::|   .|.:.|    ...|.|:.||.::|.|           |:.||
Zfish   271 READGVWVYNRSCYPIFIKSATLDNPDSR----TLLVHKVFPGFSIKAFDFEKAGSLQRPNDHEF 331

  Fly   410 AALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 462
                ||....||          |:::|||||||..|.||.::|.|||:|:..|
Zfish   332 ----SQQPRTGF----------TVQISFVKGWGQCYTRQFISSCPCWLEVIFN 370

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	33/95 (35%)
		MH2_SMAD_2_3	285..475	CDD:199826	63/192 (33%)
smad7	NP_778257.2	MH1_SMAD_7	36..152	CDD:199818	33/104 (32%)
		MH2_SMAD_7	200..370	CDD:199825	64/215 (30%)