Protein Alignment Smox and smad2

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001276944.1
• Gene: smad2 / 30639
• ZFINID: ZDB-GENE-990603-7
• Length: 468
• Species: Danio rerio
• Alignment Length: 540
• Identity: 303/540 - (56%)
• Similarity: 346/540 - (64%)
• Gaps: 129/540 - (23%)

  Fly     1 MLPFTPQVVKRLLALKK----------GNEDNSVEGKWSEKAVKNLVKKIKKNSQLEELERAIST 55
            :|||||.||||||..||          |.|.|..|.||.|||||:||||:||..||:|||:||:|
Zfish     4 ILPFTPPVVKRLLGWKKSASGSSGAGGGGEQNGQEEKWCEKAVKSLVKKLKKTGQLDELEKAITT 68

  Fly    56 QNCQTRCVTVP------------------------------RSKPAPAGEHLRKGLPHVIYCRLW 90
            ||..|:|||:|                              ||.........|||||||||||||
Zfish    69 QNRNTKCVTIPSNCSEIWGLSTPNTIEQWDTSGLYSYPDQTRSLDGRLQVSHRKGLPHVIYCRLW 133

  Fly    91 RWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIELSILVPKSLPTPPDSIVDY-PLDNHT 154
            |||||.|.:||:.::.|||||:|:|:|:|:|||||:::|..:|.|..:|...:.:.:. |||::|
Zfish   134 RWPDLHSHHELRAIETCEYAFNLKKDEVCVNPYHYQRVETPVLPPVLVPRHTEILTELPPLDDYT 198

  Fly   155 HQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSVSSSASSTPATAAGGGGGPSSSSSSSSSAAS 219
            :.||.||::...|      .||
Zfish   199 NSIPENTNFPTGI------EPP------------------------------------------- 214

  Fly   220 AYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPPPGYMSEDGDPIDPNDNMNM----------S 274
                                    .:.||.  ||||||:||||:..|...|.:|          |
Zfish   215 ------------------------NNYIPE--TPPPGYISEDGEASDQQMNQSMDTGSPAELSPS 253

  Fly   275 RLTP---PADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLGLLS 336
            .|:|   ..|..||.|.||||||||:|||||.||||||||||||:||||||||||||||||||||
Zfish   254 TLSPVNHGMDLQPVTYSEPAFWCSIAYYELNQRVGETFHASQPSLTVDGFTDPSNSERFCLGLLS 318

  Fly   337 NVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHPATVCKIPPGCNL 401
            |||||..||.||||||:|||||||||||||||||||:||||||||||||||||||||||||||||
Zfish   319 NVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNL 383

  Fly   402 KIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 466
            ||||||||||||:|||:||||||||||||||||||||||||||||||||||||||||||||||||
Zfish   384 KIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQ 448

  Fly   467 WLDRVLTQMGSPRLPCSSMS 486
            |||:||||||||.:.|||||
Zfish   449 WLDKVLTQMGSPSVRCSSMS 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	77/162 (48%)
		MH2_SMAD_2_3	285..475	CDD:199826	176/189 (93%)
smad2	NP_001276944.1	MH1_SMAD_2_3	8..173	CDD:199815	79/164 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	224..254		10/29 (34%)
		MH2_SMAD_2_3	267..457	CDD:199826	176/189 (93%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	349	1.000	Domainoid score	I990
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	579	1.000	Inparanoid score	I996
OMA	1	1.010	-	-		QHG48607
OrthoDB	1	1.010	-	-		D274383at33208
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	1	1.000	-	-		otm24510
orthoMCL	1	0.900	-	-		OOG6_104703
Panther	1	1.100	-	-	O	PTHR13703
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	1	1.500	-	-
	13	13.340