Protein Alignment Smox and Smad1

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: XP_006255456.1
• Gene: Smad1 / 25671
• RGDID: 3030
• Length: 483
• Species: Rattus norvegicus
• Alignment Length: 531
• Identity: 269/531 - (50%)
• Similarity: 324/531 - (61%)
• Gaps: 98/531 - (18%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTRCVT 64
            :..||...|||||..|:|:|    |.||:||||..||||: ||...:||||:|:|.....:.|||
  Rat     6 LFSFTSPAVKRLLGWKQGDE----EEKWAEKAVDALVKKLKKKKGAMEELEKALSCPGQPSNCVT 66

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:|||||:.||:.|..:::|:||||||||::|
  Rat    67 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRVE 131

  Fly   130 LSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYN-----AAIIRSASLSPPQYMELGGAGPVSV 189
            ..:|.|.                   .:|.:::||     .|..|:...:.| :|.|....|.|.
  Rat   132 SPVLPPV-------------------LVPRHSEYNPQHSLLAQFRNLGQNEP-HMPLNATFPDSF 176

  Fly   190 SSSAS----STPATAAGGGGGPSSS----SSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSS 246
            ....|    .:|.::.....|.|||    |.:||...|.:|..
  Rat   177 QQPHSHPFPQSPNSSYPNSPGSSSSTYPHSPTSSDPGSPFQMP---------------------- 219

  Fly   247 IPNTGTPPPGY------MSEDG-DPIDPNDNMNMSRLTPP-----------------------AD 281
               ..||||.|      |::|| .|:|    .||:.:|.|                       ||
  Rat   220 ---ADTPPPAYLPPEDPMAQDGSQPMD----TNMTNMTAPTLPAEINRGGEVSCRSPCESLLSAD 277

  Fly   282 AAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSE-RFCLGLLSNVNRNEVVE 345
            ...|.|.||..||||.|||||.||||.||||..|:.|||||||||:: |||||||||||||..:|
  Rat   278 VQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIE 342

  Fly   346 QTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFA 410
            .|||||||||.|||:||||:|||||||||||||.|||..:|:||.||||||.||:||||||||||
  Rat   343 NTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFA 407

  Fly   411 ALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQM 475
            .||:|||:.|||.||:||:||||||||||||||||.||.|||||||||:||:|||||||:|||||
  Rat   408 QLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQM 472

  Fly   476 GSPRLPCSSMS 486
            |||..|.||:|
  Rat   473 GSPHNPISSVS 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	69/123 (56%)
		MH2_SMAD_2_3	285..475	CDD:199826	149/190 (78%)
Smad1	XP_006255456.1	MH1_SMAD_1_5_9	9..132	CDD:199814	71/126 (56%)
		PRK10263	<133..>244	CDD:236669	33/159 (21%)
		MH2_SMAD_1_5_9	283..483	CDD:199822	156/199 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274383at33208
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820