Protein Alignment Smox and tag-68

DIOPT Version :10

• Sequence 1: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_492746.2
• Gene: tag-68 / 172930
• WormBaseID: WBGene00006445
• Length: 415
• Species: Caenorhabditis elegans
• Alignment Length: 525
• Identity: 97/525 - (18%)
• Similarity: 151/525 - (28%)
• Gaps: 217/525 - (41%)

  Fly    24 VEGKW--------SEKAVKNLVKKIKKNSQLEELE---RAISTQNCQTR-CVTVP----RSKPAP 72
            ||..|        .|:..:....::.:....|::|   :|:.:....:: |...|    |.:..|
 Worm    16 VERLWRRRLLVTSDERRARRRFLRLMRGFDAEDVEVIRKAVESDGVDSKACAPGPPMDERVEEDP 80

  Fly    73 AGEHLRKGL-PHV--------IYCRLWRWPDLQ---SQNELKPLDHCEYA-FHLRKEEI-CINPY 123
            ..|.  .|| |.:        :.|:||||.|||   :.:.|:.|..|.:. ..:....: |.|||
 Worm    81 PDED--SGLIPQIDRPMSMPYLCCKLWRWKDLQVDAALHRLEALPWCRFGRVTINNATVSCCNPY 143

  Fly   124 HYKKIELSILVPKSLPTPPDSIVDYPLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVS 188
            ||                                       |..||
 Worm   144 HY---------------------------------------ALWIR------------------- 150

  Fly   189 VSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFG--------QNMDSQSSVLS--- 242
                    |.|    .||....|...:|:......:...:..|        ...|::.|.|.
 Worm   151 --------PET----NGGDDDGSEDKNSSVPQNNHRSSLIGNGHITYRHRDHTHDAEMSKLPKIL 203

  Fly   243 VGS-------SIPNTGTPPPGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEP-AFWCSISYY 299
            .|.       |:|| .|||   :.:|..|.....:.:      |.|.....:||. ..|..::.|
 Worm   204 AGELPDRPPPSVPN-ATPP---LPDDSPPCTSRSSQD------PDDLIHYHHHESNRSWAKMTRY 258

  Fly   300 ELNTRVGETFHASQPSITVD---------------------------------GFTDP------- 324
            |...::|:|.....|...|.                                 |.|:|
 Worm   259 ERKEQIGDTVWLHGPFAAVGVLSKSVHDAQLECSPWDLKNEVSFALIRQADPIGSTNPEDVWLYN 323

  Fly   325 SNSERFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHP 389
            |.:....|.:..||:.   .:.|.|.:..|..:....|||.|...:.....|:.|:
 Worm   324 SGTRPLFLSMTPNVSS---TKDTLRRLSPGYCIRVHRGEVSASAPASERTKVRRPS--------- 376

  Fly   390 ATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTP 454
                |.|              ||..|:                :.:|..||||..|.|..:|..|
 Worm   377 ----KDP--------------ALAQQN----------------LVISVGKGWGPNYSRLYLTDIP 407

  Fly   455 CWIEL 459
            |..|:
 Worm   408 CRYEV 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	32/135 (24%)
		MH2_SMAD_2_3	285..475	CDD:199826	41/216 (19%)
tag-68	NP_492746.2	MH1_SMAD_6_7	14..152	CDD:199813	35/203 (17%)
		MH2	251..415	CDD:469593	39/208 (19%)