Protein Alignment Smox and Smad5

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001157513.1
• Gene: Smad5 / 17129
• MGIID: 1328787
• Length: 465
• Species: Mus musculus
• Alignment Length: 506
• Identity: 268/506 - (52%)
• Similarity: 330/506 - (65%)
• Gaps: 67/506 - (13%)

  Fly     1 MLPFTPQVVKRLLALKKGNEDNSVEGKWSEKAVKNLVKKI-KKNSQLEELERAISTQNCQTRCVT 64
            :..||...|||||..|:|:|    |.||:||||..||||: ||...:||||:|:|:....::|||
Mouse     7 LFSFTSPAVKRLLGWKQGDE----EEKWAEKAVDALVKKLKKKKGAMEELEKALSSPGQPSKCVT 67

  Fly    65 VPRSKPAPAGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEICINPYHYKKIE 129
            :|||.........|||||||||||:||||||||.:||||||.||:.|..:::|:||||||||::|
Mouse    68 IPRSLDGRLQVSHRKGLPHVIYCRVWRWPDLQSHHELKPLDICEFPFGSKQKEVCINPYHYKRVE 132

  Fly   130 LSILVPKSLP-----TPPDS-IVDY-PLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAG-P 186
            ..:|.|..:|     .|..| :|.: .|.::...:|.|..:           |..:.:...|. |
Mouse   133 SPVLPPVLVPRHNEFNPQHSLLVQFRNLSHNEPHMPQNATF-----------PDSFHQPNNAPFP 186

  Fly   187 VSVSSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTG 251
            :|.:|....:||::.      ..:|.:||...|.:|                        :| ..
Mouse   187 LSPNSPYPPSPASST------YPNSPASSGPGSPFQ------------------------LP-AD 220

  Fly   252 TPPPGYMSEDGDPIDPNDNM------NMSRLTPPA----DAAPVMYHEPAFWCSISYYELNTRVG 306
            ||||.||..| |.:.|:::.      ||...|.|:    |..||.|.||..||||.|||||.|||
Mouse   221 TPPPAYMPPD-DQMAPDNSQPMDTSSNMIPQTMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVG 284

  Fly   307 ETFHASQPSITVDGFTDPSNSE-RFCLGLLSNVNRNEVVEQTRRHIGKGVRLYYIGGEVFAECLS 370
            |.||||..|:.|||||||||:: |||||||||||||..:|.|||||||||.|||:||||:|||||
Mouse   285 EAFHASSTSVLVDGFTDPSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLS 349

  Fly   371 DSSIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRM 435
            ||||||||.|||..:|:||.||||||..|:||||||||||.||:|||:.||||||:||:||||||
Mouse   350 DSSIFVQSRNCNFHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRM 414

  Fly   436 SFVKGWGAEYRRQTVTSTPCWIELHLNGPLQWLDRVLTQMGSPRLPCSSMS 486
            ||||||||||.||.|||||||||:||:|||||||:||||||||..|.||:|
Mouse   415 SFVKGWGAEYHRQDVTSTPCWIEIHLHGPLQWLDKVLTQMGSPLNPISSVS 465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	70/123 (57%)
		MH2_SMAD_2_3	285..475	CDD:199826	149/190 (78%)
Smad5	NP_001157513.1	MH1_SMAD_1_5_9	10..133	CDD:199814	72/126 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	163..251		26/130 (20%)
		MH2_SMAD_1_5_9	265..465	CDD:199822	156/199 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D274383at33208
OrthoFinder	1	1.000	-	-		FOG0000630
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X373
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.820