Protein Alignment Smox and smad6a

DIOPT Version :9

• Sequence 1: NP_001285006.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Sequence 2: NP_001019981.2
• Gene: smad6a / 116992
• ZFINID: ZDB-GENE-011015-1
• Length: 456
• Species: Danio rerio
• Alignment Length: 448
• Identity: 124/448 - (27%)
• Similarity: 182/448 - (40%)
• Gaps: 127/448 - (28%)

  Fly    26 GKWSEKAVKN----LVKKIKKNSQLEELERAISTQ-NCQTRCVTVPRSKPAPAGEHLRKGLPHVI 85
            |..:|:.:|.    .:||:|..| |:.|..|:.:| ...:.||.|.::: ...|.||..  |..:
Zfish   122 GAVTEQELKKCTYAFLKKLKDKS-LDVLLEAVESQGGMPSGCVLVSQTE-VRIGGHLVS--PQYL 182

  Fly    86 YCRLWRWPDLQSQNELKPLDHCEYAFHLRKEE---ICINPYHYKKIELSILVPKSLPTPPDSIVD 147
            .|||:|||||:..:.||||.||:   ..|.|:   :|.||:||.:    :..|....|||
Zfish   183 LCRLFRWPDLRLSSLLKPLCHCQ---SFRAEDSQTLCCNPHHYSR----LCGPVKDDTPP----- 235

  Fly   148 YPLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSVSSSASSTPATAAGGGGGPSSSSS 212
             |..:|...:|.:...|      :||....|:|               |.||.:.||.....|.:
Zfish   236 -PPYSHLSPLPEHKPLN------SSLPMLPYIE---------------TEATRSAGGLSQDYSDA 278

  Fly   213 SSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPPPGYMSEDGDPIDPNDNMNMSRLT 277
            |.|.:           |..||
Zfish   279 SMSPS-----------SLAQN-------------------------------------------- 288

  Fly   278 PPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVDGFTDPSNSERFCLGLLSNVNRNE 342
                          .||:::|:||.||||..:.....|:::  |.|.......|||||....|:.
Zfish   289 --------------HWCNVAYWELRTRVGRLYPVHDASLSI--FYDLPQGTGLCLGLLPLSPRST 337

  Fly   343 VVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSPNCNQRYGWHP---ATVCKIPPGCNLKIF 404
            .|::||..||.|:.|......|:|...|...|||.||....    ||   .||.::.||.::|:|
Zfish   338 SVQRTRGKIGHGILLSKEPDGVWAYNRSQHPIFVNSPTLEH----HPYLSLTVRRVMPGYSIKVF 398

  Fly   405 NNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLN 462
            :.::...:...|.....|..|...   ::|:||.||||..|.||.:||.|||:|:.||
Zfish   399 DYEKSCQMQPASHPVHPEGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLN 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Smox	NP_001285006.1	MH1_R-SMAD	7..130	CDD:199812	39/111 (35%)
		MH2_SMAD_2_3	285..475	CDD:199826	62/181 (34%)
smad6a	NP_001019981.2	MH1_SMAD_6	118..229	CDD:199817	39/117 (33%)
		MH2	281..454	CDD:294046	66/251 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810