DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF93

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_112495.2 Gene:ZNF93 / 81931 HGNCID:13169 Length:620 Species:Homo sapiens


Alignment Length:311 Identity:99/311 - (31%)
Similarity:143/311 - (45%) Gaps:33/311 - (10%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 CLEDLQLFAQLEDL-------SGERLPMEMELLNPGSEYDLLELVNGAL--QQRNTTEHKP--TD 79
            |:|..:.|.|...|       :||: |...|......:|      :.||  .:|..|..||  .|
Human   175 CIECGKAFNQFSTLITHKKIHTGEK-PYICEECGKAFKY------SSALNTHKRIHTGEKPYKCD 232

  Fly    80 MCKPK--RTPTTKRH---RTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQL 139
            .|...  .:.|..:|   .|..|.:.|:.|.:.|:::..|..||..||.|||:.|.||||.|.|.
Human   233 KCDKAFIASSTLSKHEIIHTGKKPYKCEECGKAFNQSSTLTKHKKIHTGEKPYKCEECGKAFNQS 297

  Fly   140 NKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPC------LATDCHLSFHS-I 197
            :.|..|...||.|:|:.|:.|||.|:|:..||.|:|:|||||||.|      ......||.|. |
Human   298 STLTKHKKIHTGEKPYVCEECGKAFKYSRILTTHKRIHTGEKPYKCNKCGKAFIASSTLSRHEFI 362

  Fly   198 HARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFP 262
            |..:.|.|.....:.. .....|...::..|....:.|..|.:.......||.|.:.|..::.:.
Human   363 HMGKKHYKCEECGKAF-IWSSVLTRHKRVHTGEKPYKCEECGKAFKYSSTLSSHKRSHTGEKPYK 426

  Fly   263 CPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            |  .||||.|.::|.|..|:|.||.::|:.|..|...|.:.|:..:|.|:|
Human   427 C--EECGKAFVASSTLSKHEIIHTGKKPYKCEECGKAFNQSSSLTKHKKIH 475

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 14/24 (58%)
C2H2 Zn finger 129..149 CDD:275368 9/19 (47%)
zf-H2C2_2 142..166 CDD:290200 11/23 (48%)
COG5048 151..>264 CDD:227381 35/119 (29%)
C2H2 Zn finger 157..177 CDD:275368 10/19 (53%)
C2H2 Zn finger 185..206 CDD:275368 7/27 (26%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
C2H2 Zn finger 263..285 CDD:275368 10/21 (48%)
C2H2 Zn finger 293..313 CDD:275368 6/19 (32%)
ZNF93NP_112495.2 KRAB 4..62 CDD:214630
KRAB 6..43 CDD:279668
C2H2 Zn finger 147..167 CDD:275368
COG5048 170..612 CDD:227381 99/311 (32%)
C2H2 Zn finger 175..195 CDD:275368 5/19 (26%)
C2H2 Zn finger 203..223 CDD:275368 5/25 (20%)
zf-H2C2_2 215..238 CDD:290200 8/22 (36%)
C2H2 Zn finger 231..251 CDD:275368 4/19 (21%)
zf-H2C2_2 244..268 CDD:290200 6/23 (26%)
C2H2 Zn finger 259..279 CDD:275368 6/19 (32%)
zf-H2C2_2 272..296 CDD:290200 14/23 (61%)
C2H2 Zn finger 287..307 CDD:275368 9/19 (47%)
zf-H2C2_2 300..324 CDD:290200 11/23 (48%)
C2H2 Zn finger 315..335 CDD:275368 10/19 (53%)
zf-H2C2_2 328..350 CDD:290200 12/21 (57%)
C2H2 Zn finger 343..363 CDD:275368 4/19 (21%)
C2H2 Zn finger 371..391 CDD:275368 1/20 (5%)
zf-H2C2_2 384..408 CDD:290200 4/23 (17%)
C2H2 Zn finger 399..419 CDD:275368 5/19 (26%)
zf-H2C2_2 412..435 CDD:290200 9/24 (38%)
C2H2 Zn finger 427..447 CDD:275368 10/21 (48%)
zf-H2C2_2 440..464 CDD:290200 9/23 (39%)
C2H2 Zn finger 455..475 CDD:275368 6/19 (32%)
zf-H2C2_2 467..492 CDD:290200 3/9 (33%)
C2H2 Zn finger 483..503 CDD:275368
zf-H2C2_2 495..520 CDD:290200
C2H2 Zn finger 511..531 CDD:275368
zf-H2C2_2 524..547 CDD:290200
C2H2 Zn finger 539..559 CDD:275368
zf-H2C2_2 551..576 CDD:290200
C2H2 Zn finger 567..587 CDD:275368
zf-H2C2_2 580..602 CDD:290200
C2H2 Zn finger 595..615 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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