Protein Alignment CG2120 and ZNF226

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001027544.1
• Gene: ZNF226 / 7769
• HGNCID: 13019
• Length: 803
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 86/252 - (34%)
• Similarity: 126/252 - (50%)
• Gaps: 31/252 - (12%)

  Fly    69 QRNTTEHKP--TDMC-----KPKRTPTTKRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKP 126
            ||..|..||  .|.|     :.....:.:|..|..|.:.|:.|.:.|..:.||.||:..||.|||
Human   382 QRLHTGEKPFKCDACGKSFSRNSHLQSHQRVHTGEKPYKCEECGKGFICSSNLYIHQRVHTGEKP 446

  Fly   127 HVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCH 191
            :.|.||||||.:.:.|:.|...||.|:.:.|.:|||||..::.|..|:|:|||||||.|  .:|.
Human   447 YKCEECGKGFSRPSSLQAHQGVHTGEKSYICTVCGKGFTLSSNLQAHQRVHTGEKPYKC--NECG 509

  Fly   192 LSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHY 256
            .||.    |..|.::.....|...|                :.|.:|.:..:...||.||.|.|.
Human   510 KSFR----RNSHYQVHLVVHTGEKP----------------YKCEICGKGFSQSSYLQIHQKAHS 554

  Fly   257 NQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            .::.|.|  .|||:.|..:|.|:.||:.||.::|:.|..|...|.|:::.|.|.::|
Human   555 IEKPFKC--EECGQGFNQSSRLQIHQLIHTGEKPYKCEECGKGFSRRADLKIHCRIH 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	7/19 (37%)
		zf-H2C2_2	113..138	CDD:290200	16/24 (67%)
		C2H2 Zn finger	129..149	CDD:275368	9/19 (47%)
		zf-H2C2_2	142..166	CDD:290200	11/23 (48%)
		COG5048	151..>264	CDD:227381	34/112 (30%)
		C2H2 Zn finger	157..177	CDD:275368	9/19 (47%)
		C2H2 Zn finger	185..206	CDD:275368	6/20 (30%)
		C2H2 Zn finger	235..255	CDD:275368	7/19 (37%)
		C2H2 Zn finger	263..285	CDD:275368	9/21 (43%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
ZNF226	NP_001027544.1	KRAB	8..67	CDD:214630
		C2H2 Zn finger	256..302	CDD:275370
		SUF4-like	306..>357	CDD:411020
		C2H2 Zn finger	309..334	CDD:411020
		C2H2 Zn finger	309..329	CDD:275368
		C2H2 Zn finger	337..357	CDD:411020
		C2H2 Zn finger	337..357	CDD:275368
		COG5048	359..774	CDD:227381	86/252 (34%)
		C2H2 Zn finger	365..385	CDD:275368	2/2 (100%)
		C2H2 Zn finger	393..413	CDD:275368	3/19 (16%)
		C2H2 Zn finger	421..441	CDD:275368	7/19 (37%)
		C2H2 Zn finger	449..469	CDD:275368	9/19 (47%)
		C2H2 Zn finger	477..497	CDD:275368	9/19 (47%)
		C2H2 Zn finger	505..525	CDD:275368	6/25 (24%)
		C2H2 Zn finger	533..553	CDD:275368	7/19 (37%)
		C2H2 Zn finger	561..581	CDD:275368	9/21 (43%)
		C2H2 Zn finger	589..609	CDD:275368	6/19 (32%)
		C2H2 Zn finger	617..637	CDD:275368
		C2H2 Zn finger	645..665	CDD:275368
		C2H2 Zn finger	673..693	CDD:275368
		C2H2 Zn finger	701..721	CDD:275368
		C2H2 Zn finger	729..749	CDD:275368
		C2H2 Zn finger	757..777	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	781..803

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910