Protein Alignment CG2120 and ZNF16

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001025147.2
• Gene: ZNF16 / 7564
• HGNCID: 12947
• Length: 682
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 92/260 - (35%)
• Similarity: 132/260 - (50%)
• Gaps: 19/260 - (7%)

  Fly    69 QRNTTEHKP---TDMCKP--KRTPTTKRHRT-TG-KDHTCDICDRRFSEAYNLRIHKMTHTDEKP 126
            ||..|..||   .|..||  :.:...|.||. || |.:.|..|.:.||::.:|..|:..||.|||
Human   396 QRVHTGEKPYECNDCGKPFSRVSNLIKHHRVHTGEKPYKCSDCGKAFSQSSSLIQHRRIHTGEKP 460

  Fly   127 HVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCH 191
            |||..|||.|...:.||.|.:.||.|:|::|.:|||.|.:::.|..|:.:|||:|||.|  .:|.
Human   461 HVCNVCGKAFSYSSVLRKHQIIHTGEKPYRCSVCGKAFSHSSALIQHQGVHTGDKPYAC--HECG 523

  Fly   192 LSF----HSIHARRIHTKLRHAAQTDPDPEHPLAE---QEQRDTSALS-FTCPVCSRVLTDQCYL 248
            .:|    :.|..:|:||..:....|:.......:.   |.||..:.|. ..|..|.:.......|
Human   524 KTFGRSSNLILHQRVHTGEKPYECTECGKTFSQSSTLIQHQRIHNGLKPHECNQCGKAFNRSSNL 588

  Fly   249 SIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            ..|.|.|..::.:.|  .||||.|..:|.|..|||.||.:||:.|..|...|.::|...||.::|
Human   589 IHHQKVHTGEKPYTC--VECGKGFSQSSHLIQHQIIHTGERPYKCSECGKAFSQRSVLIQHQRIH 651

  Fly   314  313
            Human   652  651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	14/24 (58%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	12/23 (52%)
		COG5048	151..>264	CDD:227381	33/120 (28%)
		C2H2 Zn finger	157..177	CDD:275368	7/19 (37%)
		C2H2 Zn finger	185..206	CDD:275368	7/24 (29%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..285	CDD:275368	11/21 (52%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
ZNF16	NP_001025147.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..43
		Necessary for transcription activation	62..210
		COG5048	<160..369	CDD:227381
		C2H2 Zn finger	187..203	CDD:275368
		C2H2 Zn finger	211..231	CDD:275368
		C2H2 Zn finger	239..259	CDD:275368
		C2H2 Zn finger	267..287	CDD:275368
		Required for nuclear localization	268..393
		C2H2 Zn finger	295..315	CDD:275368
		COG5048	303..675	CDD:227381	92/260 (35%)
		C2H2 Zn finger	323..343	CDD:275368
		Required for nuclear localization	341..373
		C2H2 Zn finger	351..371	CDD:275368
		C2H2 Zn finger	379..399	CDD:275368	2/2 (100%)
		C2H2 Zn finger	407..427	CDD:275368	6/19 (32%)
		C2H2 Zn finger	435..455	CDD:275368	6/19 (32%)
		C2H2 Zn finger	463..483	CDD:275368	8/19 (42%)
		Required for nuclear localization	473..503		12/29 (41%)
		C2H2 Zn finger	491..511	CDD:275368	7/19 (37%)
		C2H2 Zn finger	519..539	CDD:275368	5/21 (24%)
		C2H2 Zn finger	547..567	CDD:275368	4/19 (21%)
		C2H2 Zn finger	575..595	CDD:275368	5/19 (26%)
		C2H2 Zn finger	603..623	CDD:275368	11/21 (52%)
		C2H2 Zn finger	631..651	CDD:275368	6/19 (32%)
		C2H2 Zn finger	659..679	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000