DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF7

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001336738.1 Gene:ZNF7 / 7553 HGNCID:13139 Length:707 Species:Homo sapiens


Alignment Length:310 Identity:94/310 - (30%)
Similarity:130/310 - (41%) Gaps:60/310 - (19%)


- Green bases have known domain annotations that are detailed below.


  Fly    26 CLEDLQLFAQLEDL-------SGERLPMEMELLNPGSEYDLLELVNGALQQRNTTEH------KP 77
            |.|..:.|:|...|       :|||            .|...|......|.....:|      :.
Human   357 CRECGKAFSQQSQLVRHQRTHTGER------------PYPCKECGKAFSQSSTLAQHQRMHTGEK 409

  Fly    78 TDMCKPKRTPTTKRHR---TTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQL 139
            ..:.|...:|:...|:   ...|...||.|.:.|.....|..|::.||.|||:.|.:|.|.|...
Human   410 AQILKASDSPSLVAHQRIHAVEKPFKCDECGKAFRWISRLSQHQLIHTGEKPYKCNKCTKAFGCS 474

  Fly   140 NKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHS----IHAR 200
            ::|..|..|||.|:|.|||.|||||...::|..|:|:|||||||.|  .||..:|..    |:.:
Human   475 SRLIRHQRTHTGEKPFKCDECGKGFVQGSHLIQHQRIHTGEKPYVC--NDCGKAFSQSSSLIYHQ 537

  Fly   201 RIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQ 265
            |||           ..|.|             :.|..|.:..:....|:||.:.|..:|.:.|  
Human   538 RIH-----------KGEKP-------------YECLQCGKAFSMSTQLTIHQRVHTGERPYKC-- 576

  Fly   266 PECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVHER 315
            .||||.|...|.|..|||.|...:|:.|..|...|.|.|...:|.::|.|
Human   577 NECGKAFSQNSTLFQHQIIHAGVKPYECSECGKAFSRSSYLIEHQRIHTR 626

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 11/24 (46%)
C2H2 Zn finger 129..149 CDD:275368 6/19 (32%)
zf-H2C2_2 142..166 CDD:290200 15/23 (65%)
COG5048 151..>264 CDD:227381 37/116 (32%)
C2H2 Zn finger 157..177 CDD:275368 10/19 (53%)
C2H2 Zn finger 185..206 CDD:275368 8/24 (33%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
C2H2 Zn finger 263..285 CDD:275368 11/21 (52%)
C2H2 Zn finger 293..313 CDD:275368 6/19 (32%)
ZNF7NP_001336738.1 KRAB 25..86 CDD:214630
PHA02693 64..>137 CDD:333460
COG5048 239..696 CDD:227381 94/310 (30%)
C2H2 Zn finger 246..265 CDD:275368
C2H2 Zn finger 273..293 CDD:275368
C2H2 Zn finger 301..321 CDD:275368
C2H2 Zn finger 329..349 CDD:275368
C2H2 Zn finger 357..377 CDD:275368 5/19 (26%)
C2H2 Zn finger 385..405 CDD:275368 3/19 (16%)
C2H2 Zn finger 436..456 CDD:275368 6/19 (32%)
C2H2 Zn finger 464..484 CDD:275368 6/19 (32%)
C2H2 Zn finger 492..512 CDD:275368 10/19 (53%)
C2H2 Zn finger 520..540 CDD:275368 6/21 (29%)
C2H2 Zn finger 548..568 CDD:275368 5/19 (26%)
C2H2 Zn finger 576..596 CDD:275368 11/21 (52%)
C2H2 Zn finger 604..624 CDD:275368 6/19 (32%)
C2H2 Zn finger 657..677 CDD:275368
C2H2 Zn finger 685..705 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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