Protein Alignment CG2120 and ZNF492

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_065906.1
• Gene: ZNF492 / 57615
• HGNCID: 23707
• Length: 531
• Species: Homo sapiens
• Alignment Length: 289
• Identity: 88/289 - (30%)
• Similarity: 135/289 - (46%)
• Gaps: 45/289 - (15%)

  Fly    26 CLEDLQLFAQLEDLSGERLPMEMELLNPGSE-YDLLELVNGALQQRNTTEHKPTDMCKPKRTPTT 89
            |.|..:.|.:|..|:..:      :::.|.: |...|......|..|.|.|
Human   199 CEECGKAFNRLSHLTTHK------IIHTGKKPYKCEECGKAFNQSANLTTH-------------- 243

  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERP 154
            ||..|..|.:.|:.|.|.||::..|..||:.|..|||:.|.||||.|.|.:.|..|.:.||.|:.
Human   244 KRIHTGEKPYKCEECGRAFSQSSTLTAHKIIHAGEKPYKCEECGKAFSQSSTLTTHKIIHTGEKF 308

  Fly   155 HKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHP 219
            :||:.|||.|...::||.|:|:|:|||||.|  .:|..:|........|.:: ||.:.
Human   309 YKCEECGKAFSQLSHLTTHKRIHSGEKPYKC--EECGKAFKQSSTLTTHKRI-HAGEK------- 363

  Fly   220 LAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIA 284
                        .:.|.|||:..:...:|:.|.:.|..::.:.|  .||||.|..:|:|..|:|.
Human   364 ------------FYKCEVCSKAFSRFSHLTTHKRIHTGEKPYKC--EECGKAFNLSSQLTTHKII 414

  Fly   285 HTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            ||.::|:.|..|...|.:.|...:|..:|
Human   415 HTGEKPYKCEECGKAFNQSSTLSKHKVIH 443

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	8/19 (42%)
		zf-H2C2_2	113..138	CDD:290200	13/24 (54%)
		C2H2 Zn finger	129..149	CDD:275368	9/19 (47%)
		zf-H2C2_2	142..166	CDD:290200	11/23 (48%)
		COG5048	151..>264	CDD:227381	30/112 (27%)
		C2H2 Zn finger	157..177	CDD:275368	9/19 (47%)
		C2H2 Zn finger	185..206	CDD:275368	4/20 (20%)
		C2H2 Zn finger	235..255	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..285	CDD:275368	10/21 (48%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
ZNF492	NP_065906.1	KRAB	<1..32	CDD:214630
		COG5048	138..522	CDD:227381	88/289 (30%)
		C2H2 Zn finger	143..163	CDD:275368
		zf-H2C2_2	155..179	CDD:290200
		C2H2 Zn finger	171..191	CDD:275368
		zf-H2C2_2	183..208	CDD:290200	3/8 (38%)
		C2H2 Zn finger	199..219	CDD:275368	5/25 (20%)
		zf-H2C2_2	211..236	CDD:290200	4/30 (13%)
		C2H2 Zn finger	227..247	CDD:275368	7/33 (21%)
		zf-H2C2_2	239..264	CDD:290200	11/38 (29%)
		C2H2 Zn finger	255..275	CDD:275368	8/19 (42%)
		C2H2 Zn finger	283..303	CDD:275368	9/19 (47%)
		C2H2 Zn finger	311..331	CDD:275368	9/19 (47%)
		zf-H2C2_2	323..348	CDD:290200	13/26 (50%)
		C2H2 Zn finger	339..359	CDD:275368	4/22 (18%)
		C2H2 Zn finger	367..387	CDD:275368	6/19 (32%)
		zf-H2C2_2	379..403	CDD:290200	8/25 (32%)
		C2H2 Zn finger	395..415	CDD:275368	10/21 (48%)
		zf-H2C2_2	408..432	CDD:290200	9/23 (39%)
		C2H2 Zn finger	423..443	CDD:275368	5/19 (26%)
		C2H2 Zn finger	451..471	CDD:275368
		zf-H2C2_2	463..488	CDD:290200
		C2H2 Zn finger	479..499	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000